Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161472 | 0.87 | KDM4E (0.41) | NPC1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL14579885 | 0.87 | KDM4E (0.52) | NPC1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8808484 | 0.87 | KDM4E (0.52) | NPC1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL23155090 | 0.85 | KDM4E (0.40) | NPC1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL19603987 | 0.85 | KDM4E (0.42) | NPC1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL19269156 | 0.85 | KDM4E (0.41) | NPC1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL25712529 | 0.84 | KDM4E (0.46) | NPC1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL15788790 | 0.84 | TP53 (0.43) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL23762520 | 0.83 | KDM4E (0.39) | NPC1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL17695455 | 0.83 | KDM4E (0.46) | NPC1RAB9AKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230193361-A1 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-22 | — | — | US | disclosed |
| WO-2023107673-A2 | CLEAVABLE DISULFIDE LINKERS AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2022271970-A1 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | Singular Genomics Systems, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |
| US-11352502-B2 | Polymeric tandem dyes with linker groups | Sony Group Corporation (JP) | 2022-06-07 | — | — | US | disclosed |
| US-20210285953-A1 | POLYMERIC DYES HAVING A BACKBONE COMPRISING ORGANOPHOSPHATE UNITS | Sony Group Corporation (JP) | 2021-09-16 | — | — | US | disclosed |
| US-20210253864-A1 | POLYMERIC TANDEM DYES WITH LINKER GROUPS | Sony Group Corporation (JP) | 2021-08-19 | — | — | US | disclosed |
| US-11001886-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | AGILENT TECHNOLOGIES, INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20190127790-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2019-05-02 | — | — | US | disclosed |
| US-10041115-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | LASERGEN, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20170327886-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | LASERGEN, INC. (US) | 2017-11-16 | — | — | US | disclosed |
| US-9689035-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | LASERGEN, INC. (US) | 2017-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352502-B2 | Polymeric tandem dyes with linker groups | CHRM1, IK, TMT1A | NPC1 4754/4885RAB9A 3055/4885KDM4E 3566/4885 |
| US-20190127790-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | RNGTT, NT5C3B, NSUN2 | NPC1 4039/4885RAB9A 4048/4885KDM4E 1347/4885 |
| US-10041115-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | RNGTT, NT5C3B, NSUN2 | NPC1 4046/4885RAB9A 4039/4885KDM4E 1357/4885 |
| US-11001886-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | RNGTT, NT5C3B, NSUN2 | NPC1 4046/4885RAB9A 4039/4885KDM4E 1357/4885 |
| US-20170327886-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | RNGTT, NT5C3B, NSUN2 | NPC1 4039/4885RAB9A 4048/4885KDM4E 1347/4885 |
| US-20210253864-A1 | POLYMERIC TANDEM DYES WITH LINKER GROUPS | CHRM1, IK, TMT1A | NPC1 4754/4885RAB9A 3055/4885KDM4E 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.