Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19033143 | 0.87 | ALDH1A1 (0.51) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL6371197 | 0.85 | MAPK1 (0.51) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL21444940 | 0.83 | AKR1C3 (0.49) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL14866257 | 0.81 | MAPT (0.48) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL1662886 | 0.78 | ALDH1A1 (0.65) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL28461970 | 0.78 | ALDH1A1 (0.49) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL6520 | 0.77 | TDP1 (0.58) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL29445159 | 0.77 | TDP1 (0.58) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL1852678 | 0.77 | GPR35 (0.56) | MAPTMAPK1KMT2AKDM4EAKR1C3 | |
| SCHEMBL11199415 | 0.77 | ALDH1A1 (0.54) | MAPTMAPK1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9689035-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | LASERGEN, INC. (US) | 2017-06-27 | — | — | US | disclosed |