Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19033295 | 1.00 | ADRA1A (0.53) | ADRA1AEPHX2TSHRLMNANFKB1 | |
| SCHEMBL16330318 | 0.94 | SLC22A6 (0.48) | ADRA1AEPHX2TSHRLMNAPMP22 | |
| SCHEMBL25662202 | 0.90 | SLC22A6 (0.44) | ADRA1AEPHX2TSHRLMNAPMP22 | |
| SCHEMBL16217880 | 0.89 | RECQL (0.60) | TSHRPMP22RECQLFAAHGAA | |
| SCHEMBL19477806 | 0.87 | RECQL (0.54) | TSHRRECQLFAAHGAAMEN1 | |
| SCHEMBL19477807 | 0.87 | RECQL (0.54) | TSHRRECQLFAAHGAAMEN1 | |
| SCHEMBL24961509 | 0.85 | PTPN1 (0.59) | ADRA1AEPHX2TSHRLMNANFKB1 | |
| SCHEMBL12296709 | 0.85 | PTPN1 (0.59) | ADRA1AEPHX2TSHRLMNANFKB1 | |
| SCHEMBL22838868 | 0.85 | PTPN1 (0.59) | ADRA1AEPHX2TSHRLMNANFKB1 | |
| SCHEMBL20750809 | 0.85 | PTPN1 (0.59) | ADRA1AEPHX2TSHRLMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688737-B2 | Protease stabilized acylated insulin analogues | NOVO NORDISK A/S (DK) | 2017-06-27 | — | — | US | disclosed |