Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808624 | 1.00 | PTPN1 (0.59) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL6888800 | 1.00 | PTPN1 (0.59) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL13694070 | 1.00 | PTPN1 (0.59) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL22838868 | 1.00 | PTPN1 (0.59) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL20750809 | 1.00 | PTPN1 (0.59) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL24961509 | 1.00 | PTPN1 (0.59) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL7602768 | 1.00 | PTPN1 (0.59) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL15680097 | 0.98 | PTPN1 (0.56) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL8750020 | 0.95 | PTPN1 (0.63) | PTPN1FAAHLMNAPMP22TSHR | |
| SCHEMBL10056657 | 0.95 | PTPN1 (0.63) | PTPN1FAAHLMNAPMP22TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000949-A1 | SOLID COMPOSITIONS COMPRISING A PCSK9 INHIBITOR AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID | NOVO NORDISK AS (DK) | 2023-01-05 | — | — | US | disclosed |
| US-11352406-B2 | Insulin derivatives and the medical uses hereof | NOVO NORDISK A/S (DK) | 2022-06-07 | — | — | US | disclosed |
| US-20210094999-A1 | Novel Acylated Insulin Analogues and Uses Thereof | NOVO NORDISK AS (DK) | 2021-04-01 | — | — | US | disclosed |
| US-10570184-B2 | GLP-1/glucagon receptor co-agonists for medical use | NOVO NORDISK A/S (DK) | 2020-02-25 | — | — | US | disclosed |
| US-20190112348-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | NOVO NORDISK AS (DK) | 2019-04-18 | — | — | US | disclosed |
| US-20170101454-A1 | GLP-1/Glucagon Receptor Co-Agonists for Medical Use | NOVO NORDISK A/S (DK) | 2017-04-13 | — | — | US | disclosed |
| WO-2011117415-A1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK A/S (DK) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101454-A1 | GLP-1/Glucagon Receptor Co-Agonists for Medical Use | GLP1R, GCGR, GIPR | PTPN1 654/4885FAAH 739/4885LMNA 3923/4885 |
| US-11352406-B2 | Insulin derivatives and the medical uses hereof | IAPP, INSR, IRS1 | PTPN1 1919/4885FAAH 1629/4885LMNA 2035/4885 |
| US-20230000949-A1 | SOLID COMPOSITIONS COMPRISING A PCSK9 INHIBITOR AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID | PCSK9, EGFR, PCSK6 | PTPN1 83/4885FAAH 2825/4885LMNA 2016/4885 |
| US-10570184-B2 | GLP-1/glucagon receptor co-agonists for medical use | GLP1R, GCGR, GIPR | PTPN1 645/4885FAAH 755/4885LMNA 3976/4885 |
| US-20210094999-A1 | Novel Acylated Insulin Analogues and Uses Thereof | IAPP, GPR119, INSR | PTPN1 3051/4885FAAH 491/4885LMNA 2378/4885 |
| US-20190112348-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | IAPP, IDE, LIPE | PTPN1 4022/4885FAAH 179/4885LMNA 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.