Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 8/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19477806 | 1.00 | RECQL (0.54) | RECQLGAAFAAHPAOXHDAC3 | |
| SCHEMBL16250314 | 0.98 | RECQL (0.56) | RECQLGAAFAAHPAOXHDAC3 | |
| SCHEMBL16217880 | 0.93 | RECQL (0.60) | RECQLGAAFAAHHDAC3HDAC1 | |
| SCHEMBL14241014 | 0.89 | RECQL (0.47) | RECQLGAAFAAHPAOXMEN1 | |
| SCHEMBL13203022 | 0.88 | RECQL (0.54) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL17087645 | 0.87 | FAAH (0.67) | GAAFAAHMEN1KMT2ADNM1 | |
| SCHEMBL21641891 | 0.87 | FAAH (0.57) | RECQLGAAFAAHPAOXMEN1 | |
| SCHEMBL17002034 | 0.87 | FAAH (0.67) | GAAFAAHMEN1KMT2ADNM1 | |
| SCHEMBL19033296 | 0.87 | ADRA1A (0.53) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL19033295 | 0.87 | ADRA1A (0.53) | RECQLGAAFAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187760-A1 | MANNOSE-TARGETED COMPOSITIONS | GENEVANT SCIENCES GMBH (CH) | 2023-10-05 | — | — | WO | disclosed |
| WO-2021113820-A1 | CONJUGATES AND METHODS FOR TREATING LIVER FIBROSIS | GENEVANT SCIENCES GMBH (CH) | 2021-06-10 | — | — | WO | disclosed |
| WO-2020191207-A1 | THERAPEUTIC METHODS FOR TREATING HEPATITIS B | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-09-24 | — | — | WO | disclosed |
| WO-2019051257-A2 | METHODS FOR TREATING HEPATITIS B INFECTIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-03-14 | — | — | WO | disclosed |
| WO-2017177326-A1 | TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2017-10-19 | — | — | WO | disclosed |