Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.62 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935833 | 0.89 | KIF11 (0.56) | KIF11PTPN5ESR1ESR2ALDH1A1 | |
| SCHEMBL612731 | 0.87 | ALDH1A1 (0.58) | KIF11ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL8064676 | 0.87 | ESR1 (0.72) | KIF11PTPN5ESR1ESR2ALDH1A1 | |
| SCHEMBL14489508 | 0.86 | KIF11 (0.52) | KIF11PTPN5ESR1ESR2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL7131897 | 0.85 | TSHR (0.55) | KIF11ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL21888606 | 0.84 | KIF11 (0.45) | KIF11PTPN5ESR1ESR2TSHR | |
| SCHEMBL21370135 | 0.83 | KIF11 (0.48) | KIF11PTPN5ESR1ESR2ALDH1A1 | |
| SCHEMBL21370227 | 0.81 | KIF11 (0.47) | KIF11ALDH1A1CYP2C9CYP1A2HSD17B10 | |
| SCHEMBL11982096 | 0.81 | NPC1 (0.59) | KIF11ALDH1A1PTPN1CYP1A2HSD17B10 | |
| SCHEMBL8582134 | 0.79 | ESR1 (0.48) | KIF11ESR1ESR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9691520-B2 | Method for preparing polymer-nanoparticles having core-shell structure by uniformly coating polymer on metal and inorganic particles, polymer-nanoparticles prepared thereby, and polymer-nanoparticle composite comprising same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2017-06-27 | — | — | US | disclosed |