Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24859932 | 0.78 | MMP9 (0.47) | MMP9MMP2TLR2MMP1MMP3 | |
| SCHEMBL13744807 | 0.73 | ANPEP (0.49) | MMP2TLR2MMP1MMP3ANPEP | |
| SCHEMBL7225611 | 0.72 | MMP2 (0.45) | MMP9MMP2TLR2CPA1CPA2 | |
| SCHEMBL7225608 | 0.72 | MMP2 (0.45) | MMP9MMP2TLR2CPA1CPA2 | |
| SCHEMBL16856622 | 0.71 | MMP2 (0.56) | MMP9MMP2MMP1MMP3ANPEP | |
| SCHEMBL22695988 | 0.71 | MMP2 (0.56) | MMP9MMP2MMP1MMP3ANPEP | |
| SCHEMBL2327179 | 0.71 | KDM4E (0.38) | — | |
| SCHEMBL6048015 | 0.71 | KDM4E (0.38) | — | |
| SCHEMBL18818106 | 0.70 | CYP3A4 (0.52) | MMP9MMP2TLR2MMP1MMP3 | |
| SCHEMBL14230866 | 0.70 | MMP2 (0.48) | MMP9MMP2TLR2ANPEPHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9687562-B2 | Polymers having therapeutically active agents conjugated thereto, processes of preparing same and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-06-27 | — | — | US | disclosed |