Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | APEX1 | P27695 | 1/20 | 0.71 |
| ▸ | POLA1 | P09884 | 4/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | SOD1 | P00441 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15588782 | 0.84 | KARS1 (1.00) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL28617784 | 0.84 | KARS1 (1.00) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL15723549 | 0.83 | SOD1 (0.67) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL15588775 | 0.77 | SOD1 (0.77) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL7024094 | 0.77 | SOD1 (0.77) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL14696167 | 0.77 | SOD1 (0.77) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL17927225 | 0.76 | KARS1 (0.71) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL31255935 | 0.76 | PDE4D (0.85) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL5061925 | 0.76 | KARS1 (0.71) | KARS1POLBAPEX1POLA1RXRA | |
| SCHEMBL280198 | 0.75 | POLA1 (1.00) | KARS1POLBAPEX1POLA1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688810-B2 | Resin, resin composition and method for producing the same, and toner using this resin composition | FUJIFILM CORPORATION (JP) | 2017-06-27 | — | — | US | disclosed |