Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
| ▸ | RXRA | P19793 | 1/20 | 0.67 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.67 |
| ▸ | CDK2 | P24941 | 1/20 | 0.67 |
| ▸ | RXRB | P28702 | 1/20 | 0.67 |
| ▸ | RXRG | P48443 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | POLA1 | P09884 | 4/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | SOD1 | P00441 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15588782 | 1.00 | KARS1 (1.00) | KARS1POLBAPEX1RXRACCNE1 | |
| SCHEMBL19034284 | 0.84 | KARS1 (0.71) | KARS1POLBAPEX1RXRACCNE1 | |
| SCHEMBL15588775 | 0.83 | SOD1 (0.77) | KARS1POLBAPEX1RXRACCNE1 | |
| SCHEMBL14696167 | 0.83 | SOD1 (0.77) | KARS1POLBAPEX1RXRACCNE1 | |
| SCHEMBL7024094 | 0.83 | SOD1 (0.77) | KARS1POLBAPEX1RXRACCNE1 | |
| SCHEMBL5061925 | 0.82 | KARS1 (0.71) | KARS1POLBAPEX1RXRACCNE1 | |
| SCHEMBL17927225 | 0.82 | KARS1 (0.71) | KARS1POLBAPEX1RXRACCNE1 | |
| SCHEMBL31255935 | 0.82 | PDE4D (0.85) | KARS1POLBAPEX1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL14653170 | 0.81 | KARS1 (1.00) | KARS1POLBAPEX1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL18019015 | 0.81 | KARS1 (1.00) | KARS1POLBAPEX1RXRACCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113265381-B | Separated CYP450 protein, coding gene thereof and application thereof | 首都医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-113265381-A | Separated CYP450 protein, coding gene thereof and application thereof | 首都医科大学 | 2021-08-17 | — | — | CN | disclosed |