Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ZDHHC7 | Q9NXF8 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22591738 | 1.00 | LMNA (0.48) | LMNAZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL14977291 | 0.94 | ZDHHC7 (0.43) | LMNAZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL17485794 | 0.92 | TSHR (0.48) | LMNAZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL765874 | 0.92 | TSHR (0.45) | LMNAZDHHC7KDM4EMAPK1HIF1A | |
| SCHEMBL29099712 | 0.88 | ZDHHC7 (0.47) | LMNAZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL29099721 | 0.88 | ZDHHC7 (0.47) | LMNAZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL29475789 | 0.86 | FAAH (0.44) | LMNAZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL18638052 | 0.84 | TSHR (0.57) | LMNAKDM4EMAPK1CA2 | |
| SCHEMBL2105851 | 0.84 | TSHR (0.57) | LMNAKDM4EMAPK1CA2 | |
| SCHEMBL14397158 | 0.83 | PAOX (0.39) | LMNAZDHHC7KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688669-B2 | Oxazolidinones as modulators of mGluR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-27 | — | — | US | disclosed |