SCHEMBL1903565

SCHEMBL1903565

NC(=O)C[C@H](NC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1N)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 7/20 0.41
▸ CA2 P00918 4/20 0.39
▸ CA9 Q16790 4/20 0.39
▸ CA12 O43570 3/20 0.39
▸ CA1 P00915 3/20 0.39
▸ GAA P10253 1/20 0.38
▸ LGALS3 P17931 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20817264 1.00 PYGB (0.41) PYGBCA2CA9CA12CA1
SCHEMBL23066316 1.00 PYGB (0.41) PYGBCA2CA9CA12CA1
SCHEMBL31206852 0.90 CA12 (0.45) PYGBCA2CA9CA12CA1
SCHEMBL22346509 0.89 CA12 (0.48) PYGBCA2CA9CA12CA1
SCHEMBL670576 0.87 PYGB (0.44) PYGBCA2CA9CA12CA1
SCHEMBL2848040 0.87 PYGB (0.44) PYGBCA2CA9CA12CA1
SCHEMBL4006332 0.87 PYGB (0.44) PYGBCA2CA9CA12CA1
SCHEMBL309481 0.81 CA1 (0.47) PYGBCA2CA9CA1GAA
SCHEMBL4345382 0.81 CA1 (0.47) PYGBCA2CA9CA1GAA
SCHEMBL2169970 0.81 CA1 (0.47) PYGBCA2CA9CA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024006542-A1 ANTI-ROR1 ANTIBODIES AND ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-ROR1 ANTIBODIES OR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-ROR1 ANTIBODIES AND ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. (US) 2024-01-04 — — WO disclosed
WO-2023244517-A1 INTERLEUKIN-2 PRODRUGS MERCK SHARP & DOHME LLC (US) 2023-12-21 — — WO disclosed
EP-4143233-A1 METHODS OF PRODUCING FULL-LENGTH ANTIBODIES USING E.COLI Sutro Biopharma, Inc. (US) 2023-03-08 — — EP disclosed
EP-4139340-A1 HUMAN INTERLEUKIN-2 CONJUGATES BIASED FOR THE INTERLEUKIN-2 RECEPTOR BETA GAMMAC DIMER AND CONJUGATED TO A NONPEPTIDIC, WATER-SOLUBLE POLYMER Merck Sharp & Dohme LLC (US) 2023-03-01 — — EP disclosed
US-20220127630-A1 Brassica Plants Producing Elevated Levels of Polyunsaturated Fatty Acids CARGILL, INCORPORATED (US) 2022-04-28 — — US disclosed
EP-3980423-A1 5H-PYRROLO[3,2-D]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF Sutro Biopharma, Inc. (US) 2022-04-13 — — EP disclosed
EP-3962951-A1 ANTI-BCMA ANTIBODY CONJUGATES Sutro Biopharma, Inc. (US) 2022-03-09 — — EP disclosed
EP-3923991-A1 COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES Ambrx, Inc. (US) 2021-12-22 — — EP disclosed
WO-2021222719-A1 METHODS OF PRODUCING FULL-LENGTH ANTIBODIES USING E.COLI SUTRO BIOPHARMA, INC. (US) 2021-11-04 — — WO disclosed
WO-2021216478-A1 HUMAN INTERLEUKIN-2 CONJUGATES BIASED FOR THE INTERLEUKIN-2 RECEPTOR BETA GAMMAc DIMER AND CONJUGATED TO A NONPEPTIDIC, WATER-SOLUBLE POLYMER MERCK SHARP & DOHME CORP. (US) 2021-10-28 — — WO disclosed
EP-1771573-A2 BIOSYNTHETIC POLYPEPTIDES UTILIZING NON-NATURALLY ENCODED AMINO ACIDS AMBRX, INC. (US) 2007-04-11 — — EP disclosed
WO-2006133088-A2 IMPROVED HUMAN INTERFERON MOLECULES AND THEIR USES AMBRX, INC. (US) 2006-12-14 — — WO disclosed
WO-2006133089-A2 IMPROVED HUMAN INTERFERON MOLECULES AND THEIR USES AMBRX, INC. (US) 2006-12-14 — — WO disclosed
WO-2006132969-A2 INCORPORATION OF NON-NATURALLY ENCODED AMINO ACIDS INTO PROTEINS AMBRX, INC. (US) 2006-12-14 — — WO disclosed
EP-1718339-A2 MODIFIED HUMAN INTERFERON POLYPEPTIDES AND THEIR USES Ambrx, Inc. (US) 2006-11-08 — — EP disclosed
EP-1718664-A2 MODIFIED HUMAN FOUR HELICAL BUNDLE POLYPEPTIDES AND THEIR USES Ambrx, Inc. (US) 2006-11-08 — — EP disclosed
WO-2006091231-A2 BIOSYNTHETIC POLYPEPTIDES UTILIZING NON-NATURALLY ENCODED AMINO ACIDS AMBRX, INC. (US) 2006-08-31 — — WO disclosed
WO-2006073846-A2 METHODS FOR EXPRESSION AND PURIFICATION OF RECOMBINANT HUMAN GROWTH HORMONE AMBRX, INC. (US) 2006-07-13 — — WO disclosed
WO-2005074524-A2 MODIFIED HUMAN INTERFERON POLYPEPTIDES AND THEIR USES AMBRX, INC. (US) 2005-08-18 — — WO disclosed
WO-2005074650-A2 MODIFIED HUMAN FOUR HELICAL BUNDLE POLYPEPTIDES AND THEIR USES AMBRX, INC. (US) 2005-08-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127630-A1 Brassica Plants Producing Elevated Levels of Polyunsaturated Fatty Acids FADS2, ELOVL3, SCD PYGB 1774/4885CA2 4157/4885CA9 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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