SCHEMBL4345382

SCHEMBL4345382

CC(=O)N[C@H]1C(N[C@@H](CC(N)=O)C(=O)O)O[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ CA9 Q16790 2/20 0.47
▸ ALDH1A1 P00352 2/20 0.46
▸ THRB P10828 1/20 0.46
▸ MAPK1 P28482 2/20 0.46
▸ MMP12 P39900 2/20 0.41
▸ MMP9 P14780 1/20 0.41
▸ PYGB P11216 3/20 0.40
▸ GAA P10253 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ CD69 Q07108 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL309481 1.00 CA1 (0.47) CA1CA2CA9ALDH1A1THRB
SCHEMBL2169970 1.00 CA1 (0.47) CA1CA2CA9ALDH1A1THRB
SCHEMBL8653916 0.90 ALDH1A1 (0.48) CA1CA2CA9ALDH1A1THRB
SCHEMBL1115743 0.87 ALDH1A1 (0.50) CA1CA2CA9ALDH1A1THRB
SCHEMBL308568 0.87 ALDH1A1 (0.50) CA1CA2CA9ALDH1A1THRB
SCHEMBL309095 0.87 ALDH1A1 (0.50) CA1CA2CA9ALDH1A1THRB
SCHEMBL308565 0.87 ALDH1A1 (0.50) CA1CA2CA9ALDH1A1THRB
SCHEMBL31206852 0.84 CA12 (0.45) CA1CA2CA9PYGBGAA
SCHEMBL22346509 0.83 CA12 (0.48) CA1CA2CA9PYGBGAA
SCHEMBL23066316 0.81 PYGB (0.41) CA1CA2CA9PYGBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260009800-A1 METHODS OF DIAGNOSIS AND GUIDING TREATMENT OF VULVOVAGINAL SYMPTOMS AND FEMALE SEXUAL DYSFUNCTION UNIV ARIZONA (US) 2026-01-08 — — US claimed
US-20250164507-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CARDIOMYOPATHY IN A FELINE Société des Produits Nestlé S.A. (CH) 2025-05-22 — — US claimed
US-20230015727-A1 Methods, Kits and Compositions for Diagnosing and Treating Renal Disease HILL'S PET NUTRITION, INC. (US) 2023-01-19 — — US claimed
EP-2991683-A1 CONJUGATES OF A GLYCOPROTEIN OR A GLYCAN WITH A TOXIC PAYLOAD Glykos Finland Oy (FI) 2016-03-09 — — EP claimed
WO-2014177771-A1 CONJUGATES OF A GLYCOPROTEIN OR A GLYCAN WITH A TOXIC PAYLOAD GLYKOS FINLAND OY (FI) 2014-11-06 — — WO claimed
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH UNIV CALIFORNIA (US) 2026-03-19 — — US disclosed
US-12553902-B2 Methods, kits and compositions for diagnosing and treating renal disease HILL'S PET NUTRITION, INC. (US) 2026-02-17 — — US disclosed
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF OSPEDALE SAN RAFFAELE S.R.L. (IT) 2026-01-22 — — US disclosed
US-20260009800-A1 METHODS OF DIAGNOSIS AND GUIDING TREATMENT OF VULVOVAGINAL SYMPTOMS AND FEMALE SEXUAL DYSFUNCTION UNIV ARIZONA (US) 2026-01-08 — — US disclosed
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM UNIV CALIFORNIA (US) 2025-12-11 — — US disclosed
US-12491217-B2 Compositions and methods for promoting healthy neural development in an unborn baby THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-09 — — US disclosed
US-20250164507-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CARDIOMYOPATHY IN A FELINE Société des Produits Nestlé S.A. (CH) 2025-05-22 — — US disclosed
EP-2053403-A2 Affinity fishing for ligands and proteins receptors Novo Nordisk A/S (DK) 2009-04-29 — — EP disclosed
EP-1588173-B1 AFFINITY FISHING FOR LIGANDS AND PROTEINS RECEPTORS NOVO NORDISK AS (DK) 2008-11-26 — — EP disclosed
US-20060257875-A1 Affinity screening using \"one-bead-one-compound\" libraries CARLSBERG A/S (DK) 2006-11-16 — — US disclosed
US-20040142379-A1 Affinity fishing for ligands and proteins receptors CARLSBERG RESEARCH LABORATORY (DK) 2004-07-22 — — US disclosed
WO-1998052129-A1 CONSTITUTIONAL ANALYSIS OF PROTEIN DOMAINS MACQUARIE RESEARCH LTD. (AU) 1998-11-19 — — WO disclosed
EP-0425019-B1 Methods and compositions employing certain lysozymes and endoglycosidases PROCTER & GAMBLE (US) 1995-01-11 — — EP disclosed
US-5041236-A Antimicrobial methods and compositions employing certain lysozymes and endoglycosidases THE PROCTER & GAMBLE COMPANY (US) 1991-08-20 — — US disclosed
EP-0425019-A1 Methods and compositions employing certain lysozymes and endoglycosidases THE PROCTER & GAMBLE COMPANY (US) 1991-05-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM CYP27A1, LIPC, CYP46A1 CA1 2438/4885CA2 1492/4885CA9 1211/4885
US-20260009800-A1 METHODS OF DIAGNOSIS AND GUIDING TREATMENT OF VULVOVAGINAL SYMPTOMS AND FEMALE SEXUAL DYSFUNCTION SHBG, GNRHR, STIM2 CA1 1855/4885CA2 1683/4885CA9 782/4885
US-20260076944-A1 COMPOSITIONS AND METHODS FOR PROMOTING BRAIN HEALTH IDO1, INMT, IDO2 CA1 2403/4885CA2 2828/4885CA9 2293/4885
US-12553902-B2 Methods, kits and compositions for diagnosing and treating renal disease GLS, KYNU, AADAT CA1 491/4885CA2 381/4885CA9 301/4885
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF ASNS, AARS1, NARS1 CA1 4348/4885CA2 4025/4885CA9 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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