Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.50 |
| ▸ | HINT1 | P49773 | 1/20 | 0.50 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19242512 | 1.00 | HPGD (0.52) | HPGDTLR7HINT1FUT5STING1 | |
| SCHEMBL21562192 | 1.00 | HPGD (0.52) | HPGDTLR7HINT1FUT5STING1 | |
| SCHEMBL19882058 | 1.00 | HPGD (0.52) | HPGDTLR7HINT1FUT5STING1 | |
| SCHEMBL20059041 | 1.00 | HPGD (0.52) | HPGDTLR7HINT1FUT5STING1 | |
| SCHEMBL20056927 | 0.92 | HINT1 (0.49) | HPGDHINT1FUT5STING1PDE3B | |
| SCHEMBL20057162 | 0.89 | TAAR1 (0.49) | HPGDHINT1FUT5STING1PDE3B | |
| SCHEMBL4323450 | 0.88 | ADORA3 (0.53) | HPGDTLR7HINT1STING1PDE3B | |
| SCHEMBL9200583 | 0.88 | ADORA3 (0.53) | HPGDTLR7HINT1STING1PDE3B | |
| SCHEMBL98906 | 0.88 | ADORA3 (0.53) | HPGDTLR7HINT1STING1PDE3B | |
| SCHEMBL98907 | 0.88 | ADORA3 (0.53) | HPGDTLR7HINT1STING1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688715-B2 | Synthetic pGpG analogs, methods of preparation and methods of use | Temple University—Of the Commonwealth System of Higher Education (US) | 2017-06-27 | — | — | US | disclosed |