SCHEMBL1903570

SCHEMBL1903570

C=COC(=O)c1ccccc1C(C)OC1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4E B2RXH2 2/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
STS P08842 1/20 0.33
CYP19A1 P11511 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1895796 0.78 TSHR (0.37) LMNAALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1897704 0.77 CYP3A4 (0.39) LMNAALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1897724 0.75 TSHR (0.40) ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10
SCHEMBL1899419 0.75 TSHR (0.34) ALDH1A1HSD17B10
SCHEMBL29197935 0.74 CYP3A4 (0.50) LMNAALDH1A1HSD17B10NPC1
SCHEMBL1899632 0.74 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2KDM4ENPSR1HSD17B10
SCHEMBL1901755 0.73 ALDH1A1 (0.43) LMNAALDH1A1KDM4EHSD17B10
SCHEMBL1897089 0.73 ALDH1A1 (0.36) LMNASCN1ASCN2ASCN3AALDH1A1
SCHEMBL1837157 0.72 GABRA1 (0.46) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL6552825 0.72 PTGDR2 (0.44) LMNACYP2D6ALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110101503-A1 HYPERBRANCHED POLYMER SYNTHESIZING METHOD, HYPERBRANCHED POLYMER, RESIST COMPOSITION, SEMICONDUCTOR INTEGRATED CIRCUIT, AND SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION METHOD LION CORPORATION (JP) 2011-05-05 US disclosed