SCHEMBL1903580

SCHEMBL1903580

C=Cc1ccc(-c2c(C)cccc2Br)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
RET P07949 2/20 0.36
DAPK3 O43293 1/20 0.36
JAK2 O60674 1/20 0.36
ABL1 P00519 1/20 0.36
NTRK1 P04629 1/20 0.36
FYN P06241 1/20 0.36
CSF1R P07333 1/20 0.36
MET P08581 1/20 0.36
PDGFRB P09619 1/20 0.36
FGFR1 P11362 1/20 0.36
FLT3 P36888 1/20 0.36
MAPK8 P45983 1/20 0.36
GSK3B P49841 1/20 0.36
CDK9 P50750 1/20 0.36
RPS6KA3 P51812 1/20 0.36
LIMK1 P53667 1/20 0.36
MAP2K1 Q02750 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27832336 0.77 ALDH1A1 (0.54) ALDH1A1TDP1TSHRPBRM1BRD4
SCHEMBL4537402 0.73 ALDH1A1 (0.60) ALDH1A1TDP1TSHRPBRM1
SCHEMBL17012376 0.73 ALDH1A1 (0.40) ALDH1A1TP53TDP1TSHRPBRM1
SCHEMBL4456341 0.69 CA12 (0.47) ALDH1A1TP53TDP1MAPK14TSHR
SCHEMBL8759331 0.69 ALDH1A1 (0.58) ALDH1A1TP53TDP1RETDAPK3
SCHEMBL16293471 0.69 ALDH1A1 (0.48) ALDH1A1TP53TDP1TSHR
SCHEMBL16180732 0.69 ALDH1A1 (0.50) ALDH1A1TP53TDP1RETDAPK3
SCHEMBL15971794 0.68 TP53 (0.55) ALDH1A1TP53TDP1RETTSHR
SCHEMBL14877347 0.68 ALDH1A1 (0.62) ALDH1A1TP53TDP1RETDAPK3
SCHEMBL1043440 0.68 ALDH1A1 (0.43) ALDH1A1TP53TDP1TSHRPBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110198730-A1 HYPERBRANCHED POLYMER SYNTHESIZING METHOD, HYPERBRANCHED POLYMER, RESIST COMPOSITION, SEMICONDUCTOR INTEGRATED CIRCUIT, AND SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION METHOD LION CORPORATION 2011-08-18 US disclosed
US-20110101503-A1 HYPERBRANCHED POLYMER SYNTHESIZING METHOD, HYPERBRANCHED POLYMER, RESIST COMPOSITION, SEMICONDUCTOR INTEGRATED CIRCUIT, AND SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION METHOD LION CORPORATION (JP) 2011-05-05 US disclosed
US-20080160449-A1 Photoresist polymer having nano-smoothness and etching resistance, and resist composition LION CORPORATION (JP) 2008-07-03 US disclosed
US-20070148585-A1 Hyperbranched polymer, production method therefor and resist composition containing hyperbranched polymer LION CORPORATION. 2007-06-28 US disclosed
EP-1698645-A1 HYPERBRANCHED POLYMER, PROCESS FOR PRODUCING THE SAME AND RESIST COMPOSITION CONTAINING THE HYPERBRANCHED POLYMER Lion Corporation (JP) 2006-09-06 EP disclosed