SCHEMBL19035882

SCHEMBL19035882

CN1Cc2ccccc2Cc2ccc(-c3ccc4c(c3)N(C)c3ccccc3C4)cc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 10/20 0.37
DRD5 P21918 8/20 0.37
HTR2A P28223 5/20 0.36
HRH1 P35367 4/20 0.36
HTR2C P28335 3/20 0.36
DRD3 P35462 9/20 0.36
DRD2 P14416 8/20 0.36
DRD4 P21917 6/20 0.36
HSD17B3 P37058 1/20 0.35
BRD4 O60885 1/20 0.35
CREBBP Q92793 1/20 0.35
ADRA2A P08913 3/20 0.35
ADRA2B P18089 3/20 0.35
ADRA2C P18825 3/20 0.35
SLC6A2 P23975 3/20 0.35
HTR2B P41595 3/20 0.35
LMNA P02545 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 2/20 0.35
TP53 P04637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18596812 0.94 HSD17B3 (0.36) DRD1DRD5HTR2AHRH1HTR2C
SCHEMBL20176571 0.83 HSD17B3 (0.46) DRD1DRD5DRD3DRD2DRD4
SCHEMBL2616329 0.80 DRD3 (0.48) DRD1DRD5HTR2AHRH1HTR2C
SCHEMBL22846927 0.77 HTT (0.39) HTR2AHRH1HTR2CLMNAALDH1A1
SCHEMBL12723261 0.76 MAOA (0.45) DRD1DRD5HTR2AHRH1HTR2C
SCHEMBL29351597 0.76 MAOA (0.52) DRD1DRD5HTR2AHRH1HTR2C
SCHEMBL975897 0.76 MAOA (0.52) DRD1DRD5HTR2AHRH1HTR2C
SCHEMBL13445185 0.76 DRD3 (0.39) DRD1DRD5HTR2AHRH1HTR2C
SCHEMBL27027253 0.75 DRD1 (0.45) DRD1DRD5HTR2AHRH1HTR2C
SCHEMBL20176570 0.74 NPC1 (0.47) HTR2AHRH1HTR2CLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10830935-B2 Phase difference plate, circularly polarizing plate, and image display device ZEON CORPORATION (JP) 2020-11-10 US disclosed
US-10705274-B2 Optically anisotropic layer and production method therefor, optically anisotropic laminate and production method therefor, optically anisotropic transfer body, polarization plate, and image display device ZEON COPORATION (JP) 2020-07-07 US disclosed
US-10647794-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic material ZEON CORPORATION (JP) 2020-05-12 US disclosed
US-20190202948-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICAL ANISOTROPIC BODY ZEON CORPORATION (JP) 2019-07-04 US disclosed
US-20190113667-A1 OPTICALLY ANISOTROPIC LAYER AND PRODUCTION METHOD THEREFOR, OPTICALLY ANISOTROPIC LAMINATE AND PRODUCTION METHOD THEREFOR, OPTICALLY ANISOTROPIC TRANSFER BODY, POLARIZATION PLATE, AND IMAGE DISPLAY DEVICE ZEON CORPORATION (JP) 2019-04-18 US disclosed
US-20190033213-A1 ANALYSIS PLATE, ANALYSIS METHOD, AND METHOD OF MANUFACTURING ANALYSIS PLATE ZEON CORPORATION (JP) 2019-01-31 US disclosed
US-9995865-B2 Phase difference plate, circularly polarizing plate, and image display device ZEON CORPORATION (JP) 2018-06-12 US disclosed
US-9776954-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic substance ZEON CORPORATION (JP) 2017-10-03 US disclosed
US-9690022-B2 Liquid crystal composition, phase difference plate, image display device, and method for controlling wavelength dispersion in optically anisotropic layer ZEON CORPORATION (JP) 2017-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202948-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICAL ANISOTROPIC BODY F12, PYM1, C5 DRD1 865/4885DRD5 2705/4885HTR2A 2787/4885
US-10647794-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic material C1S, F12, C5 DRD1 641/4885DRD5 2592/4885HTR2A 2189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.