SCHEMBL1903608

SCHEMBL1903608

COc1c(-c2ccccc2)cc(C)c(C)c1OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.49
PDE4A P27815 3/20 0.49
PDE4C Q08493 3/20 0.49
PDE4D Q08499 3/20 0.49
SQOR Q9Y6N5 1/20 0.46
ESR2 Q92731 1/20 0.40
KCNA3 P22001 1/20 0.40
BACE1 P56817 4/20 0.40
IKBKB O14920 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
CYP2A6 P11509 1/20 0.38
CYP2B6 P20813 1/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29143301 0.80 PDE4B (0.45) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL757781 0.78 PDE4B (0.53) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL14663128 0.78 PDE4B (0.43) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL12325398 0.77 PDE4B (0.56) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL29801662 0.77 PDE4B (0.49) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL28039230 0.77 PDE4B (0.50) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL5184749 0.76 PDE4B (0.43) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL10601269 0.76 SQOR (0.49) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL2096573 0.75 PDE4B (0.55) PDE4BPDE4APDE4CPDE4DSQOR
SCHEMBL205626 0.74 PDE4B (0.50) PDE4BPDE4APDE4CPDE4DMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016010182-A1 COMPOSITION FOR IMPROVING LIVER FUNCTION COMPRISING AS ACTIVE INGREDIENT EXOPOLYSACCHARIDE DERIVED FROM EXTRACT FROM CULTURE MEDIUM OF CERIPORIA LACERATA (주)퓨젠바이오농업회사법인 2016-01-21 WO disclosed
EP-2322470-A2 METHOD FOR MANUFACTURING UNIFORM SIZE POLYMERIC NANOPARTICLES CONTAINING POORLY SOLUBLE DRUGS Korea Research Institute of Bioscience and Biotechnology (KR) 2011-05-18 EP disclosed