Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | SI | P14410 | 4/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672070 | 0.85 | HTT (0.44) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL29672061 | 0.85 | HTT (0.44) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL10601269 | 0.85 | SQOR (0.49) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL10536048 | 0.85 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL6535979 | 0.83 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL13732796 | 0.83 | FYN (0.50) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL28984612 | 0.82 | HPGD (0.54) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL4579619 | 0.82 | HDAC4 (0.53) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL29788008 | 0.82 | HDAC4 (0.53) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL24049723 | 0.81 | PGR (0.56) | PDE4BPDE4APDE4CPDE4DGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417618-B | Process for preparing enantiomerically and diastereomerically enriched cyclobutane amines and amides | 先正达参股股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-111530311-B | Preparation method of monolithic poly (arylene ether nitrile) bipolar membrane containing corrole water dissociation catalytic group | 福建师范大学 | 2022-03-15 | — | — | CN | claimed |
| CN-109336745-B | 2,2 ', 4, 4' -biphenyl [ n ] arene, non-hole type self-adaptive crystal material thereof, and preparation method and application thereof | 上海大学 | 2021-12-03 | — | — | CN | claimed |
| CN-111530298-B | Preparation method of monolithic polyarylethersulfone ketone bipolar membrane containing phthalocyanine water dissociation catalytic group | 福建师范大学 | 2021-11-23 | — | — | CN | claimed |
| US-11053188-B2 | Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-06 | — | — | US | claimed |
| US-20200407311-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-31 | — | — | US | claimed |
| CN-109336745-A | 2,2 ', 4,4 '-biphenyl [n] aromatic hydrocarbons, its non-adaptive crystalline material of pass and preparation method and application | 上海大学 | 2019-02-15 | — | — | CN | claimed |
| CN-108400379-A | A kind of preparation of the preparation method and full battery of high security lithium ion battery diaphragm | 北京大学 | 2018-08-14 | — | — | CN | claimed |
| CN-106699520-A | Method for synthesizing 3,3',5,5'-tetramethoxyl-4,4'-biphenol | 甘肃省化工研究院 | 2017-05-24 | — | — | CN | claimed |
| CN-101709023-B | 2,2',6,6'-tetrahydroxy-3,3',5,5'-tetra-substituted biphenyl ligand and synthesis method thereof | NIPPON CHEMICAL IND | 2013-06-12 | — | — | CN | claimed |
| CN-101654401-B | Asymmetrical biphenyl compounds, medicinal compositions containing same and application of medicinal compositions | INST PHARM & TOXICOLOGY AMMS | 2013-06-05 | — | — | CN | claimed |
| CN-101898959-A | Biphenyl compound and preparation method and use thereof | UNIV JINAN | 2010-12-01 | — | — | CN | claimed |
| CN-101709023-A | 2,2',6,6'-tetrahydroxy-3,3',5,5'-tetra-substituted biphenyl ligand and synthesis method thereof | NIPPON CHEMICAL IND | 2010-05-19 | — | — | CN | claimed |
| CN-101654401-A | Asymmetrical biphenyl compounds, medicinal compositions containing same and application of medicinal compositions | POISON MED INST PLA MED ACAD | 2010-02-24 | — | — | CN | claimed |
| CN-101260074-A | Non-substituted or tetra-substituted N-acyl-carbazoles compounds and synthesizing method thereof | UNIV EAST CHINA NORMAL (CN) | 2008-09-10 | — | — | CN | claimed |
| CN-1330679-A | Plastic moulding materials which can be detected by x-ray contrast | BAYER AG (DE) | 2002-01-09 | — | — | CN | claimed |
| CN-114988991-B | Method for preparing isomeric aldehyde by hydroformylation of olefin | 中海油天津化工研究设计院有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116120154-B | Preparation method of 3,3', 5' -tetramethyl biphenol applied to electronic material | 东方飞源(山东)电子材料有限公司 | 2023-07-18 | — | — | CN | disclosed |
| WO-1995004277-A1 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMACEUTICALS CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |
| WO-1994012556-A2 | THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1994-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407311-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES | TBCB, ADORA2B, ADRA2B | PDE4B 667/4885PDE4A 1254/4885PDE4C 1213/4885 |
| US-11053188-B2 | Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides | TBCB, ADORA2B, CCNB3 | PDE4B 958/4885PDE4A 1510/4885PDE4C 1734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.