Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17141091 | 0.86 | L3MBTL1 (0.42) | GAACYP2C9CYP2C19L3MBTL1GABRA1 | |
| SCHEMBL17150396 | 0.84 | L3MBTL1 (0.46) | GAACYP2C9CYP2C19L3MBTL1GABRA1 | |
| SCHEMBL17140840 | 0.79 | L3MBTL1 (0.46) | GAACYP2C9CYP2C19L3MBTL1GABRA1 | |
| SCHEMBL31361627 | 0.75 | ALDH1A1 (0.47) | GAACYP2C9CYP2C19GABRA1GABRB2 | |
| SCHEMBL14801517 | 0.74 | MAPT (0.43) | GAACYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL20555515 | 0.74 | ALDH1A1 (0.45) | GAACYP2C9CYP2C19L3MBTL1GABRA1 | |
| SCHEMBL27034861 | 0.74 | ALDH1A1 (0.42) | GAACYP2C9CYP2C19L3MBTL1GABRA1 | |
| SCHEMBL23229761 | 0.72 | POLB (0.40) | GAACYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL20555774 | 0.71 | ALDH1A1 (0.42) | GAACYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL2519395 | 0.70 | L3MBTL1 (0.48) | GAACYP2C9CYP2C19L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208578-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2018-07-26 | — | — | US | disclosed |
| US-20170183355-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208578-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | GAA 2633/4885CYP2C9 1909/4885CYP2C19 2330/4885 |
| US-20170183355-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | GAA 2633/4885CYP2C9 1909/4885CYP2C19 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.