SCHEMBL1904046

SCHEMBL1904046

OCc1cc(Cl)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 4/20 0.71
HPGD P15428 4/20 0.71
ALOX15 P16050 4/20 0.71
CYP3A4 P08684 4/20 0.71
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
ALOX12 P18054 2/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
HSP90AA1 P07900 2/20 0.71
HTT P42858 2/20 0.71
MAPT P10636 2/20 0.71
SLC22A1 O15245 1/20 0.71
USP2 O75604 1/20 0.71
LMNA P02545 1/20 0.71
HSPD1 P10809 1/20 0.71
HSPA5 P11021 1/20 0.71
IDO1 P14902 1/20 0.71
CASP1 P29466 1/20 0.71
BLM P54132 1/20 0.71
HSPE1 P61604 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31515787 1.00 HIF1A (0.71) HIF1AHPGDALOX15CYP3A4MEN1
Heptane SCHEMBL11365624 0.87 HIF1A (0.55) HIF1AHPGDALOX15CYP3A4MEN1
Dichlorophen SCHEMBL18052 0.83 CYP3A4 (1.00) HIF1AHPGDALOX15CYP3A4MEN1
Dichlorophen SCHEMBL29524636 0.83 CYP3A4 (1.00) HIF1AHPGDALOX15CYP3A4MEN1
Dichlorophen SCHEMBL9109126 0.83 CYP3A4 (1.00) HIF1AHPGDALOX15CYP3A4MEN1
Dichlorophen SCHEMBL29349447 0.83 CYP3A4 (1.00) HIF1AHPGDALOX15CYP3A4MEN1
Dichlorophen SCHEMBL18694833 0.82 CYP3A4 (0.71) HIF1AHPGDALOX15CYP3A4MEN1
SCHEMBL2982937 0.82 ALOX15 (0.65) HIF1AHPGDALOX15CYP3A4MEN1
Dichlorophen SCHEMBL2471883 0.81 CYP3A4 (0.95) HIF1AHPGDALOX15CYP3A4MEN1
Dichlorophen SCHEMBL735904 0.81 CYP3A4 (0.95) HIF1AHPGDALOX15CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717371-B Preparation method of low-viscosity reactive flame-retardant polyether polyol, reactive flame-retardant heat-conducting polyurethane electronic pouring sealant and preparation method thereof 山东一诺威新材料有限公司 2023-11-10 CN claimed
CN-113717371-A Preparation method of low-viscosity reactive flame-retardant polyether polyol, reactive flame-retardant heat-conducting polyurethane electronic pouring sealant and preparation method thereof 山东一诺威新材料有限公司 2021-11-30 CN claimed
US-20240209016-A1 FLUORESCENT NUCLEOSIDE PHOSPHATES STEALTH LABELS BIOTECH AB (SE) 2024-06-27 US disclosed
EP-4323373-A1 FLUORESCENT NUCLEOSIDE PHOSPHATES STEALTH LABELS BIOTECH AB (SE) 2024-02-21 EP disclosed
CN-113717371-B Preparation method of low-viscosity reactive flame-retardant polyether polyol, reactive flame-retardant heat-conducting polyurethane electronic pouring sealant and preparation method thereof 山东一诺威新材料有限公司 2023-11-10 CN disclosed
US-11708364-B2 Azaindole derivatives and their use as ERK kinase inhibitors AGV DISCOVERY (FR) 2023-07-25 US disclosed
US-11708364-B2 Azaindole derivatives and their use as ERK kinase inhibitors AGV DISCOVERY (FR) 2023-07-25 US disclosed
US-11708364-B2 Azaindole derivatives and their use as ERK kinase inhibitors AGV DISCOVERY (FR) 2023-07-25 US disclosed
US-20230219995-A1 FLUORESCENT CYTOSINE ANALOGUES AND THEIR APPLICATION IN TRANSCRIPTION AND TRANSLATION STEALTH LABELS BIOTECH AB (SE) 2023-07-13 US disclosed
EP-4172170-A1 FLUORESCENT CYTOSINE ANALOGUES AND THEIR APPLICATION IN TRANSCRIPTION AND TRANSLATION STEALTH LABELS BIOTECH AB (SE) 2023-05-03 EP disclosed
EP-3196191-B1 2-ALKYLOXY BENZENE FORMYL ARYLAMINE COMPOUND AND PHARMACEUTICAL USE THEREOF UNIV FUDAN (CN) 2023-04-19 EP disclosed
US-20020119955-A1 Modified prodrug forms of AP/AMP NANOTHERAPEUTICS, INC. 2002-08-29 US disclosed
EP-1210055-A1 TWO-CONSTITUENT ELASTOMER MATERIALS BASED ON ALKYL AZIRIDINE COMPRISING A CATALYST CONSTITUENT THAT CONTAINS A BORIC ACID COMPLEX 3M Espe AG (DE) 2002-06-05 EP disclosed
WO-2002030424-A1 MODIFIED PRODRUG FORMS OF AP/AMP VION PHARMACEUTICALS, INC. (US) 2002-04-18 WO disclosed
WO-2001017483-A1 TWO-CONSTITUENT ELASTOMER MATERIALS BASED ON ALKYL AZIRIDINE COMPRISING A CATALYST CONSTITUENT THAT CONTAINS A BORIC ACID COMPLEX 3M ESPE AG (DE) 2001-03-15 WO disclosed
US-5587392-A THERAPY FOR ESTROGEN DEPENDENT DISEASES MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1996-12-24 US disclosed
EP-0684235-A1 Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-11-29 EP disclosed
CN-87100524-A Method for preserving wood 1987-09-02 CN disclosed
US-4070318-A VINYL PYRIDINE COPOLYMER RUBBER, CONDENSATION THE GENERAL TIRE & RUBBER COMPANY (US) 1978-01-24 US disclosed
US-4025553-A Production of o-hydroxybenzyl alcohols SHIONOGI & CO., LTD. (JA) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119955-A1 Modified prodrug forms of AP/AMP AP3B1, AP3D1, AP3M1 HIF1A 2058/4885HPGD 2532/4885ALOX15 3863/4885
US-20230219995-A1 FLUORESCENT CYTOSINE ANALOGUES AND THEIR APPLICATION IN TRANSCRIPTION AND TRANSLATION RNGTT, CPSF1, NSUN2 HIF1A 3005/4885HPGD 3279/4885ALOX15 3150/4885
US-11708364-B2 Azaindole derivatives and their use as ERK kinase inhibitors MAPKAPK2, MAPK1, MAPK3 HIF1A 4331/4885HPGD 653/4885ALOX15 3713/4885
US-20240209016-A1 FLUORESCENT NUCLEOSIDE PHOSPHATES RNGTT, PNP, RNMT HIF1A 3249/4885HPGD 3543/4885ALOX15 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.