Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819351 | 0.81 | TSHR (0.35) | TSHR | |
| SCHEMBL18387086 | 0.81 | TSHR (0.35) | TSHR | |
| SCHEMBL24266440 | 0.78 | — | — | |
| Methane SCHEMBL27622905 | 0.78 | TSHR (0.33) | TSHR | |
| Water SCHEMBL28283535 | 0.78 | TSHR (0.33) | TSHR | |
| SCHEMBL24482676 | 0.73 | — | — | |
| SCHEMBL25464945 | 0.70 | — | — | |
| SCHEMBL23350320 | 0.69 | — | — | |
| SCHEMBL12993101 | 0.69 | — | — | |
| SCHEMBL26216969 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286904-A1 | INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF | BRIDGENE BIOSCIENCES, INC. | 2023-09-14 | — | — | US | disclosed |
| US-11195638-B2 | Resin composition, prepreg, resin sheet, metal foil-clad laminate, and printed circuit board | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-12-07 | — | — | US | disclosed |
| US-20210363175-A1 | 9(11)-UNSATURATED NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS, INC. | 2021-11-25 | — | — | US | disclosed |
| US-20210100802-A1 | HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS | ACEA Therapeutics, Inc. (US) | 2021-04-08 | — | — | US | disclosed |
| US-20200152349-A1 | RESIN COMPOSITION, PREPREG, RESIN SHEET, METAL FOIL-CLAD LAMINATE, AND PRINTED CIRCUIT BOARD | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-05-14 | — | — | US | disclosed |
| US-10461258-B2 | Compound | IDEMITSU KOSAN CO., LTD. (JP) | 2019-10-29 | — | — | US | disclosed |
| EP-3354640-A2 | MIF INHIBITORS AND THEIR USES | Innovimmune Biotherapeutics, Inc. (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2696682-B1 | MIF INHIBITORS AND THEIR USES | INNOVIMMUNE BIOTHERAPEUTICS INC (US) | 2018-03-21 | — | — | EP | disclosed |
| US-9745613-B2 | Compounds, substrates and methods related to histone deacetylases | THE BROAD INSTITUTE, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20170186968-A1 | NOVEL COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286904-A1 | INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF | TEAD1, TEAD2, TEAD3 | TSHR 2741/4885 |
| US-10461258-B2 | Compound | CYP19A1, CYP17A1, CYP51A1 | TSHR 4566/4885 |
| US-20210363175-A1 | 9(11)-UNSATURATED NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | NR3C2, GRIN2B, HTR1B | TSHR 754/4885 |
| US-20210100802-A1 | HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS | ERBB2, EGFR, ERBB3 | TSHR 3465/4885 |
| US-20170186968-A1 | NOVEL COMPOUND | SREBF1, BRIX1, SREBF2 | TSHR 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.