SCHEMBL19044754

SCHEMBL19044754

Cc1nc(I)cc2cnccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HASPIN Q8TF76 7/20 0.38
PIM1 P11309 1/20 0.37
CLK1 P49759 1/20 0.37
CDK5 Q00535 1/20 0.37
CDK5R1 Q15078 1/20 0.37
KDM4E B2RXH2 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MAPKAPK2 P49137 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
IMPDH2 P12268 2/20 0.34
PRKCH P24723 3/20 0.34
PRKCE Q02156 3/20 0.34
PRKCQ Q04759 3/20 0.34
PRKCD Q05655 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19044424 0.85 MAOA (0.42) HASPINPIM1CLK1KDM4EMAPT
SCHEMBL19001656 0.80 HASPIN (0.39) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL18266936 0.80 CLK1 (0.39) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL19657807 0.77 LMNA (0.44) HASPINCLK1CDK5CDK5R1KDM4E
SCHEMBL18544873 0.74 CYP2A6 (0.48) KDM4ECYP1A2ALDH1A1
SCHEMBL22956783 0.73 HASPIN (0.40) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL19044619 0.73 HASPIN (0.38) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL8404559 0.72 CYP1A2 (0.52) HASPINCLK1CDK5CDK5R1KDM4E
SCHEMBL19006626 0.72 LATS1 (0.39) CYP1A2
SCHEMBL27109641 0.69 HIPK2 (0.41) HASPINCLK1CDK5CDK5R1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10367147-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-30 US disclosed
US-10312449-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-04 US disclosed
US-20190027698-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-24 US disclosed
US-9793487-B2 2017-10-17 US disclosed
US-20170186975-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed