SCHEMBL19001656

SCHEMBL19001656

Ic1cc2cnccc2c(I)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HASPIN Q8TF76 7/20 0.39
PIM1 P11309 2/20 0.39
CLK1 P49759 1/20 0.39
CDK5 Q00535 1/20 0.39
CDK5R1 Q15078 1/20 0.39
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPKAPK2 P49137 1/20 0.38
IMPDH2 P12268 2/20 0.36
HTT P42858 2/20 0.35
ALDH1A1 P00352 1/20 0.34
NCOA1 Q15788 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
PRKCH P24723 4/20 0.34
PRKCE Q02156 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001497 0.83 KDM4E (0.43) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL22956783 0.80 HASPIN (0.40) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL19044754 0.80 HASPIN (0.38) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL31219932 0.80 IMPDH2 (0.42) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL18544875 0.72 HTT (0.44) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL3298436 0.71 ALDH1A1 (0.42) KDM4ECYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL27110192 0.71 HASPIN (0.42) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL18574558 0.71 HASPIN (0.42) HASPINPIM1CLK1CDK5CDK5R1
SCHEMBL19001531 0.69 KDM4C (0.39) HASPINPIM1
SCHEMBL18459078 0.68 CLK1 (0.46) HASPINPIM1CLK1CDK5CDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-11690289-B2 Organic compound containing heterocyclic ring and having low lumo properties, and organic electroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-27 US disclosed
US-11617290-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-03-28 US disclosed
US-20220190296-A1 LIGHT-EMITTING DEVICE AND AN ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-06-16 US disclosed
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 US disclosed
US-20210320154-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-14 US disclosed
US-11056664-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-06 US disclosed
US-20210167296-A1 ORGANIC COMPOUND CONTAINING HETEROCYCLIC RING AND HAVING LOW LUMO PROPERTIES, AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2021-06-03 US disclosed
US-10916708-B2 Condensed cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-09 US disclosed
US-10756274-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-25 US disclosed
US-20180076396-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-15 US disclosed
US-9887244-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-06 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed
US-20170294587-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
US-20170294489-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
US-20170179204-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179397-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179403-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179416-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179396-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 HASPIN 4107/4885PIM1 2707/4885CLK1 1113/4885
US-10916708-B2 Condensed cyclic compound and organic light emitting device including the same C1S, C9, CCNT1 HASPIN 4741/4885PIM1 4297/4885CLK1 755/4885
US-11690289-B2 Organic compound containing heterocyclic ring and having low lumo properties, and organic electroluminescent device using the same LEF1, PPOX, LIMK1 HASPIN 4795/4885PIM1 960/4885CLK1 455/4885
US-11056664-B2 Organic light-emitting device EML4, L1CAM, OR10J3 HASPIN 4761/4885PIM1 689/4885CLK1 195/4885
US-20180076396-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNA1, CCNE2 HASPIN 3884/4885PIM1 3731/4885CLK1 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.