Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731892 | 0.85 | MCL1 (0.45) | MCL1PDE10ATDP1L3MBTL1KDM4E | |
| SCHEMBL1666642 | 0.81 | BRPF1 (0.41) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28217579 | 0.81 | MCL1 (0.41) | MCL1PDE10ATDP1L3MBTL1KDM4E | |
| SCHEMBL2937057 | 0.78 | BRPF1 (0.41) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9170208 | 0.77 | CA12 (0.52) | PDE10ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL27754085 | 0.76 | ALDH1A1 (0.37) | MCL1TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19203148 | 0.76 | LDHA (0.49) | MCL1TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL497403 | 0.76 | PDE10A (0.52) | PDE10ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL31128390 | 0.76 | PDE10A (0.52) | PDE10ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL3078467 | 0.75 | TDP1 (0.40) | MCL1PDE10ATDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906187-B2 | Method of making shoulder/nozzles with film barrier liners | COLGATE-PALMOLIVE COMPANY (US) | 2014-12-09 | — | — | US | disclosed |
| CN-102066090-B | Method of making shoulder/nozzle with membrane barrier liner | COLGATE PALMOLIVE CO | 2014-09-17 | — | — | CN | disclosed |
| EP-2321114-B1 | METHOD OF MAKING SHOULDER/NOZZELS WITH FILM BARRIER LINERS | COLGATE PALMOLIVE CO (US) | 2013-12-11 | — | — | EP | disclosed |
| EP-2321114-A1 | METHOD OF MAKING SHOULDER/NOZZELS WITH FILM BARRIER LINERS | Colgate-Palmolive Company (US) | 2011-05-18 | — | — | EP | disclosed |
| CN-102066090-A | Method of making shoulder/nozzle with membrane barrier liner | COLGATE PALMOLIVE CO | 2011-05-18 | — | — | CN | disclosed |
| US-20090324864-A1 | Method of Making Shoulder/Nozzles With Film Barrier Liners | COLGATE-PALMOLIVE (US) | 2009-12-31 | — | — | US | disclosed |
| WO-2009157931-A1 | METHOD OF MAKING SHOULDER/NOZZELS WITH FILM BARRIER LINERS | COLGATE-PALMOLIVE COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |