SCHEMBL1905112

SCHEMBL1905112

COC(=O)C(C)=CC=CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
RECQL P46063 3/20 0.48
ALOX15 P16050 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TDP1 Q9NUW8 4/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPT P10636 3/20 0.47
TSHR P16473 3/20 0.43
HCAR2 Q8TDS4 2/20 0.43
PTGS1 P23219 1/20 0.42
PTPN1 P18031 2/20 0.36
EGLN1 Q9GZT9 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
TP53 P04637 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
POLB P06746 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26664497 1.00 ALDH1A1 (0.48) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL28775708 0.84 PTGS1 (0.39) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL15978562 0.83 ALDH1A1 (0.53) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL8583353 0.83 ALDH1A1 (0.53) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL8583351 0.83 ALDH1A1 (0.53) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL8582231 0.81 ALDH1A1 (0.42) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL8582235 0.81 ALDH1A1 (0.42) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL12339277 0.81 PTGS1 (0.61) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL12192819 0.81 PTGS1 (0.61) ALDH1A1RECQLALOX15HSD17B10TDP1
SCHEMBL8503505 0.79 PTGS1 (0.75) ALDH1A1RECQLALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160161475-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION-SENSITIVE FLUORESCENT PROBES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2016-06-09 US claimed
EP-3019443-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION SENSITIVE FLUORESCENT PROBES University Of Washington Through Its Center For Commercialization (US) 2016-05-18 EP claimed
US-20160018405-A1 METHODS AND SYSTEMS FOR ANALYSIS USING POLYMER DOTS University of Washington Through it's Center for Commercialization (US) 2016-01-21 US claimed
EP-2964565-A1 WESTERN BLOT ANALYSIS USING POLYMER DOTS University Of Washington Through Its Center For Commercialization (US) 2016-01-13 EP claimed
WO-2014138312-A1 WESTERN BLOT ANALYSIS USING POLYMER DOTS UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2014-09-12 WO claimed
EP-2653867-A1 Biotracer and its use in an immunoassay King Saud University (SA) 2013-10-23 EP claimed
US-20100233816-A1 Tags Dispersible in Organic Solvents OXONICA MATERIALS INC. (US) 2010-09-16 US claimed
US-4029171-A Membrane for electroacoustic converter systems MANGER J W 1977-06-14 US claimed
EP-3277846-B1 OPTICAL PAINTING AND FLUORESCENCE-ACTIVATED SORTING OF ADHERENT CELLS UNIV WASHINGTON (US) 2024-07-10 EP disclosed
US-20240069032-A1 FUNCTIONALIZED CHROMOPHORIC POLYMER DOTS AND BIOCONJUGATES THEREOF CLEMSON UNIVERSITY RESEARCH FOUNDATION 2024-02-29 US disclosed
US-20230408526-A1 CHROMOPHORIC POLYMER DOTS UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2023-12-21 US disclosed
US-11835526-B2 Functionalized chromophoric polymer dots and bioconjugates thereof UNIVERSITY OF WASHINGTON (US) 2023-12-05 US disclosed
US-11753681-B2 Digital nucleic acid amplification using encoded particles UNIVERSITY OF WASHINGTON (US) 2023-09-12 US disclosed
US-11674964-B2 Encoded chromophoric polymer particles and methods of use thereof UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2023-06-13 US disclosed
US-20050136258-A1 Nanoparticle fluorescent probes comprised of quantum dot and hydrophobic protection structure including capping ligand and amphiphilic copolymer; biocompatibility; multiplexed imaging and detection of genes and proteins in single living cells; cancer diagnosis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-06-23 US disclosed
US-20040033206-A1 Hair treatment compositions containing at least one non-thickening amphiphilic diblock copolymer and at least one film-forming polymer which is beneficial for the hair L'OREAL (FR) 2004-02-19 US disclosed
US-5708168-A FOR TREATING OR PREVENTING NEURONAL LOSS STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1998-01-13 US disclosed
WO-1996015112-A1 AZEPINE SYNTHESIS VIA A DIELS-ALDER REACTION ACEA PHARMACEUTICALS, INC. (US) 1996-05-23 WO disclosed
US-5476933-A Condensation, ring expansion STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) 1995-12-19 US disclosed
US-4029171-A Membrane for electroacoustic converter systems MANGER J W 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040033206-A1 Hair treatment compositions containing at least one non-thickening amphiphilic diblock copolymer and at least one film-forming polymer which is beneficial for the hair DSG1, CUTA, SHH ALDH1A1 1649/4885RECQL 4553/4885ALOX15 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.