SCHEMBL1905941

SCHEMBL1905941

O=[N+]([O-])c1c(I)cc(O)cc1I

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 1/20 0.39
GPR35 Q9HC97 2/20 0.38
S100A4 P26447 2/20 0.38
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
PARP1 P09874 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11793625 0.78 GPR35 (0.48) MEN1LMNAHTTKMT2ATSHR
SCHEMBL3680628 0.76 MEN1 (0.45) MEN1LMNAHTTKMT2ATSHR
SCHEMBL31087845 0.76 MEN1 (0.45) MEN1LMNAHTTKMT2ATSHR
SCHEMBL231446 0.75 GPR35 (0.45) MEN1KMT2ATSHRALDH1A1ALOX15
SCHEMBL2466317 0.73 VCAM1 (0.40) MEN1LMNAHTTKMT2AALDH1A1
SCHEMBL13834396 0.73 GPR35 (0.53) MEN1KMT2ATSHRALDH1A1ALOX15
SCHEMBL1899575 0.71 ALDH1A1 (0.67) MEN1KMT2ATSHRALDH1A1ALOX15
SCHEMBL487041 0.71 ALDH1A1 (0.54) MEN1LMNAHTTKMT2ATSHR
SCHEMBL9820291 0.71 GAA (0.45) MEN1LMNAHTTKMT2ATSHR
SCHEMBL1901985 0.71 ALDH1A1 (0.39) MEN1LMNAHTTKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110112264-A1 PROCESS FOR PRODUCING POLYMERIZATION CATALYST OF ALKYLENE OXIDE AND POLY(ALKYLENE OXIDE) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-12 US disclosed
US-20100280197-A1 MODIFIED PARTICLE, SUPPORT, CATALYST COMPONENT FOR ADDITION POLYMERIZATION, CATALYST FOR ADDITION POLYMERIZATION, AND PROCESS FOR PRODUCING ADDITION POLYMER TAKAOKI KAZUO 2010-11-04 US disclosed
US-20030069127-A1 Modified particle,support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMTED (JP) 2003-04-10 US disclosed
EP-1275662-A1 MODIFIED PARTICLE, SUPPORT, CATALYST COMPONENT FOR ADDITION POLYMERIZATION, CATALYST FOR ADDITION POLYMERIZATION, AND PROCESS FOR PRODUCING ADDITION POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-01-15 EP disclosed