SCHEMBL1906351

SCHEMBL1906351

O=C1c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)N1c1c(Cl)cc(Cl)cc1Cl.O=C1c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)N1c1cc(Cl)cc(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.45
CA9 Q16790 3/20 0.45
CA2 P00918 3/20 0.45
CA7 P43166 3/20 0.45
CA12 O43570 2/20 0.45
DPP8 Q6V1X1 2/20 0.43
NR1H3 Q13133 5/20 0.41
DPP4 P27487 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1902124 0.92 CA1 (0.45) CA1CA9CA2CA7CA12
SCHEMBL1899173 0.88 CA1 (0.53) CA1CA9CA2CA7CA12
SCHEMBL9438238 0.74 CA1 (0.49) CA1CA9CA2CA7CA12
SCHEMBL1811288 0.73 CA9 (0.71) CA1CA9CA2CA7CA12
SCHEMBL10936072 0.73 CA9 (0.46) CA1CA9CA2CA7CA12
SCHEMBL1816383 0.72 CA9 (0.65) CA1CA9CA2CA7CA12
SCHEMBL3680527 0.68 DPP8 (0.65) CA1CA9CA2CA7CA12
SCHEMBL10934318 0.68 CA9 (0.49) CA1CA9CA2CA7CA12
SCHEMBL10976600 0.68 CA9 (0.65) CA1CA9CA2CA7CA12
SCHEMBL9977566 0.68 MAPK1 (0.38) CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496636-B1 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS COVESTRO DEUTSCHLAND AG (DE) 2019-05-15 EP disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
EP-2207844-B1 FLAME-RETARDANT POLYCARBONATES COMPRISING POLYOLS BAYER IP GMBH (DE) 2013-07-03 EP disclosed
US-20120244359-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-27 US disclosed
EP-2496639-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS Bayer MaterialScience AG (DE) 2012-09-12 EP disclosed
WO-2011054866-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER MATERIALSCIENCE AG (DE) 2011-05-12 WO disclosed