SCHEMBL1899173

SCHEMBL1899173

O=C1c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)N1c1cc(Cl)cc(Cl)c1

nearest known ligand 0.76

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.53
CA9 Q16790 3/20 0.53
CA12 O43570 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
DPP8 Q6V1X1 1/20 0.50
NR1H3 Q13133 8/20 0.47
GAPDH P04406 1/20 0.44
NR1H2 P55055 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1906351 0.88 CA1 (0.45) CA1CA9CA12CA2CA7
SCHEMBL1811288 0.83 CA9 (0.71) CA1CA9CA12CA2CA7
SCHEMBL1816383 0.82 CA9 (0.65) CA1CA9CA12CA2CA7
SCHEMBL9438238 0.80 CA1 (0.49) CA1CA9CA12CA2CA7
SCHEMBL1902124 0.77 CA1 (0.45) CA1CA9CA12CA2CA7
SCHEMBL3680527 0.77 DPP8 (0.65) CA1CA9CA12CA2CA7
SCHEMBL10976600 0.77 CA9 (0.65) CA1CA9CA12CA2CA7
SCHEMBL10934318 0.77 CA9 (0.49) CA1CA9CA12CA2CA7
SCHEMBL10424314 0.77 CA1 (0.50) CA1CA9CA12CA2CA7
SCHEMBL16425603 0.74 CA9 (0.61) CA1CA9CA12CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102725341-B Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE AG 2014-09-17 CN disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
US-20110112226-A1 Products with improved flame resistance BAYER MATERIALSCIENCE AG (DE) 2011-05-12 US disclosed
US-20090137709-A1 POLYOL-CONTAINING, FLAME-RESISTANT POLYCARBONATES, PROCESSES FOR PREPARING THE SAME AND PRODUCTS CONTAINING THE SAME BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
US-4552911-A TETRAHALOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-12 US disclosed
EP-0086353-A1 Polycarbonate moulding compounds with flame resistance BAYER AG (DE) 1983-08-24 EP disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
EP-0042561-A1 Fire-proofed moulding masses based on aromatic thermoplastic polyesters, process for its preparation and use in the production of shaped articles BAYER AG (DE) 1981-12-30 EP disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed