SCHEMBL1902124

SCHEMBL1902124

O=C1c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)N1c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.45
CA2 P00918 6/20 0.45
CA7 P43166 6/20 0.45
CA9 Q16790 3/20 0.42
CA12 O43570 2/20 0.42
GAPDH P04406 1/20 0.42
NR1H2 P55055 2/20 0.41
ALDH1A1 P00352 1/20 0.40
DPP8 Q6V1X1 1/20 0.40
NR1H3 Q13133 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1906351 0.92 CA1 (0.45) CA1CA2CA7CA9CA12
SCHEMBL10936072 0.79 CA9 (0.46) CA1CA2CA7CA9CA12
SCHEMBL1899173 0.77 CA1 (0.53) CA1CA2CA7CA9CA12
SCHEMBL9977566 0.74 MAPK1 (0.38) CA9CA12ALDH1A1
SCHEMBL465067 0.73 MGLL (0.47) ALDH1A1
SCHEMBL11022557 0.72 CA2 (0.51) CA1CA2CA7CA9CA12
SCHEMBL9188786 0.71 KMT2A (0.44) ALDH1A1
SCHEMBL1811288 0.70 CA9 (0.71) CA1CA2CA7CA9CA12
SCHEMBL1816383 0.70 CA9 (0.65) CA1CA2CA7CA9CA12
SCHEMBL9438238 0.68 CA1 (0.49) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666695-B For extruding the polycarbonate compositions of the anti-flammability with improvement of application 科思创德国股份有限公司 2016-08-17 CN disclosed
CN-102725341-B Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE AG 2014-09-17 CN disclosed
CN-101842429-B Flame retardant polycarbonate comprising a polyol BAYER MATERIALSCIENCE AG 2013-03-27 CN disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
CN-102666695-A Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE A G 2012-09-12 CN disclosed
US-20110112226-A1 Products with improved flame resistance BAYER MATERIALSCIENCE AG (DE) 2011-05-12 US disclosed
US-20090137709-A1 POLYOL-CONTAINING, FLAME-RESISTANT POLYCARBONATES, PROCESSES FOR PREPARING THE SAME AND PRODUCTS CONTAINING THE SAME BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
US-4552911-A TETRAHALOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-12 US disclosed
EP-0086353-A1 Polycarbonate moulding compounds with flame resistance BAYER AG (DE) 1983-08-24 EP disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed