Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31239024 | 1.00 | ADRA1D (0.41) | ADRA1DADRA1AMAPTRECQLTSHR | |
| SCHEMBL24297148 | 0.86 | ADRA1D (0.44) | ADRA1DADRA1AMAPTRECQLTSHR | |
| SCHEMBL31239065 | 0.86 | ADRA1A (0.50) | ADRA1DADRA1AMAPTRECQLTSHR | |
| SCHEMBL17037218 | 0.86 | ADRA1A (0.50) | ADRA1DADRA1AMAPTRECQLTSHR | |
| SCHEMBL15521514 | 0.84 | ADRA1D (0.42) | ADRA1DADRA1AMAPTRECQLTSHR | |
| SCHEMBL19066469 | 0.84 | ADRA1D (0.39) | ADRA1DADRA1AMAPTTSHRLMNA | |
| SCHEMBL4273722 | 0.84 | ADRA1D (0.39) | ADRA1DADRA1AMAPTTSHRLMNA | |
| SCHEMBL4278457 | 0.79 | KDM4E (0.53) | ADRA1DADRA1AMAPTRECQLTSHR | |
| SCHEMBL24297133 | 0.78 | PTPN11 (0.35) | MAPTLMNAABCB1ABCC1PTPN11 | |
| SCHEMBL29204552 | 0.78 | PTPN11 (0.47) | LMNAABCB1ABCC1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366573-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-07 | — | — | US | disclosed |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-21 | — | — | US | disclosed |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-21 | — | — | US | disclosed |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-10588893-B2 | Ointment containing an oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-03-17 | — | — | US | disclosed |
| US-10588893-B2 | Ointment containing an oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-03-17 | — | — | US | disclosed |
| US-20190000810-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| US-20190000810-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| EP-3397619-A1 | OINTMENT | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-11-07 | — | — | EP | disclosed |
| WO-2017115780-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017115780-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366573-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | ADRA1D 478/4885ADRA1A 491/4885MAPT 3403/4885 |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | ADRA1D 478/4885ADRA1A 491/4885MAPT 3403/4885 |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | ADRA1D 478/4885ADRA1A 491/4885MAPT 3403/4885 |
| US-10588893-B2 | Ointment containing an oxazole compound | PDE12, PDE4B, PDE4A | ADRA1D 478/4885ADRA1A 491/4885MAPT 3403/4885 |
| US-20190000810-A1 | OINTMENT | PDE12, PDE4B, PDE4A | ADRA1D 305/4885ADRA1A 262/4885MAPT 3498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.