Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336581 | 0.85 | GABRA1 (0.45) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL9170583 | 0.84 | GABRA1 (0.52) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL8974853 | 0.76 | TSHR (0.46) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL13602876 | 0.76 | KCNN2 (0.45) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL70219 | 0.75 | ALDH1A1 (0.62) | TSHRCA1CA2CYP3A4HPGD | |
| SCHEMBL29363189 | 0.75 | ALDH1A1 (0.62) | TSHRCA1CA2CYP3A4HPGD | |
| SCHEMBL28774014 | 0.75 | LMNA (0.50) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL17722822 | 0.75 | HPGD (0.61) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL31658451 | 0.75 | GABRA1 (0.76) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL301445 | 0.75 | GABRA1 (0.76) | GABRA1GABRB2GABRG2GABRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025918-A1 | KRAS G12D Inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-01-25 | — | — | US | disclosed |
| US-9695362-B1 | Color display devices | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2017-07-04 | — | — | US | disclosed |
| US-9695362-B1 | Color display devices | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2017-07-04 | — | — | US | disclosed |
| CN-101412775-B | Catalyst precursor for polymerization of propylene or combined polymerization, and preparation thereof | BEIJING JINDINGKE CHEMICAL TECHNOLOGY CO LTD | 2010-12-22 | — | — | CN | disclosed |
| CN-101139407-B | Catalyst precursor for ethylene polymerization or copolymerization and preparation method thereof | BEIJING JINDINGKE CHEMICAL TECHNOLOGY CO LTD | 2010-10-06 | — | — | CN | disclosed |
| CN-101412775-A | Catalyst activity component for polymerization of propylene or combined polymerization, catalyst precursor containing the same and preparation thereof | BEIJING JINDINGKE CHEMICAL TEC (CN) | 2009-04-22 | — | — | CN | disclosed |
| CN-101139407-A | Catalyst active component for ethylene polymerization or copolymerization and catalyst precursor comprising the active component and preparation method thereof | BEIJING JINDINGKE CHEMICAL TEC (CN) | 2008-03-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025918-A1 | KRAS G12D Inhibitors | KRAS, NRAS, HRAS | GABRA1 3975/4885GABRB2 4007/4885GABRG2 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.