Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 10/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.59 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951175 | 0.85 | AGTR1 (0.66) | AGTR1AGTR2ABCC3ABCC2 | |
| SCHEMBL7268950 | 0.81 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL21 | 0.81 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL8507705 | 0.80 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9166586 | 0.79 | AGTR1 (0.82) | AGTR1AGTR2 | |
| SCHEMBL9166569 | 0.79 | AGTR1 (0.82) | AGTR1AGTR2 | |
| SCHEMBL946900 | 0.78 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL27403298 | 0.78 | AGTR1 (0.48) | AGTR1AGTR2ABCC3ABCC2 | |
| SCHEMBL7438689 | 0.78 | AGTR1 (0.67) | AGTR1 | |
| SCHEMBL9125958 | 0.77 | AGTR1 (0.48) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051975-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF PURE EPROSARTANAND ITS PHARMACEUTICAL ACCEPTABLE SALTS | MATRIX LABORATORIES LTD (IN) | 2011-05-05 | — | — | WO | disclosed |
| WO-2010023688-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF EPROSARTAN | MATRIX LABORATORIES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |