Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256575 | 0.83 | ACHE (0.54) | MEN1KMT2ATP53CYP3A4MAPT | |
| SCHEMBL19071510 | 0.81 | ACHE (0.39) | ANPEPDPP4MAOBESR1ESR2 | |
| SCHEMBL19071419 | 0.81 | MEN1 (0.34) | ANPEPDPP4MEN1KMT2AGLA | |
| SCHEMBL19070695 | 0.78 | HSD17B1 (0.36) | MAOBTYRCYP3A4LMNAMAPK1 | |
| SCHEMBL19070272 | 0.76 | CNR1 (0.34) | ANPEPDPP4MEN1KMT2AGLA | |
| SCHEMBL19071143 | 0.75 | PBRM1 (0.46) | ANPEPDPP4MAOBTYRMEN1 | |
| SCHEMBL19070823 | 0.74 | HSD17B3 (0.32) | ANPEPDPP4HSD17B3 | |
| SCHEMBL16528479 | 0.74 | ANPEP (0.49) | ANPEPDPP4MAOBTYRMEN1 | |
| SCHEMBL10196022 | 0.72 | ANPEP (0.36) | ANPEPDPP4MAOBHSD17B3ESR1 | |
| SCHEMBL19070623 | 0.72 | ANPEP (0.36) | ANPEPDPP4MAOBHSD17B3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |