Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.54 |
| ▸ | METAP1 | P53582 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.39 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256583 | 0.85 | METAP1 (0.40) | ACHEMETAP1POLBCYP24A1CYP27A1 | |
| SCHEMBL16256576 | 0.83 | ACHE (0.56) | ACHEMETAP1CYP24A1ALDH1A1KDM4E | |
| SCHEMBL19070544 | 0.83 | ANPEP (0.38) | ACHEALDH1A1KDM4EALOX15ALOX12 | |
| SCHEMBL16256577 | 0.80 | ACHE (0.52) | ACHEMETAP1CYP24A1ALDH1A1KDM4E | |
| SCHEMBL16256586 | 0.78 | CYP24A1 (0.37) | ACHEMETAP1CYP24A1CYP27A1CYP26A1 | |
| SCHEMBL16256573 | 0.78 | CA1 (0.39) | ACHEMETAP1POLBCYP24A1CYP27A1 | |
| SCHEMBL16158067 | 0.77 | ME2 (0.53) | ACHEALDH1A1NPC1MEN1TP53 | |
| SCHEMBL16256580 | 0.77 | CYP24A1 (0.36) | ACHEMETAP1CYP24A1CYP27A1ALDH1A1 | |
| SCHEMBL16256604 | 0.75 | CYP24A1 (0.40) | ACHEMETAP1POLBCYP24A1CYP27A1 | |
| SCHEMBL19071282 | 0.75 | METAP1 (0.32) | ACHEMETAP1CYP24A1CYP27A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |