Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL11751846 | 0.98 | NPC1 (0.59) | NPC1RAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11758104 | 0.89 | MAPT (0.62) | NPC1RAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3039637 | 0.86 | ALDH1A1 (0.64) | NPC1RAB9AALDH1A1HPGDESR1 | |
| SCHEMBL10583830 | 0.86 | ALDH1A1 (0.64) | NPC1RAB9AALDH1A1HPGDLMNA | |
| SCHEMBL10581415 | 0.86 | LMNA (0.61) | NPC1RAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL14564371 | 0.84 | ERCC5 (0.55) | NPC1RAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10583762 | 0.84 | HPGD (0.59) | NPC1RAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7496934 | 0.83 | ALDH1A1 (0.53) | NPC1RAB9AALDH1A1HPGDLMNA | |
| Ethylene SCHEMBL10880928 | 0.83 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10809629 | 0.83 | L3MBTL1 (0.59) | NPC1RAB9AALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112694402-A | Synthesis method of p-acetoxystyrene | 上海博栋化学科技有限公司 | 2021-04-23 | — | — | CN | claimed |
| CN-110078722-A | A kind of thioxanthene ketone class STAT3 inhibitor maleate crystal form A and its application | 南京先进生物材料与过程装备研究院有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-109846888-A | A kind of taxol and indoles STAT3 inhibitor drug combination compositions | 南京先进生物材料与过程装备研究院有限公司 | 2019-06-07 | — | — | CN | claimed |
| CN-109485643-A | A kind of Fluorenone class STAT3 inhibitor and preparation method and application | 南京先进生物材料与过程装备研究院有限公司 | 2019-03-19 | — | — | CN | claimed |
| CN-109369627-A | Fluorenone class STAT3 inhibitor crystal form A and preparation method | 南京先进生物材料与过程装备研究院有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-109336868-A | Indoles STAT3 inhibitor and preparation method thereof | 南京先进生物材料与过程装备研究院有限公司 | 2019-02-15 | — | — | CN | claimed |
| CN-109336878-A | A kind of thioxanthene ketone class STAT3 inhibitor and its application | 南京先进生物材料与过程装备研究院有限公司 | 2019-02-15 | — | — | CN | claimed |
| CN-109293641-A | A kind of fluorenes class STAT3 inhibitor and preparation method thereof | 南京先进生物材料与过程装备研究院有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-109223758-A | A kind of taxol and fluorenes class STAT3 inhibitor drug combination compositions | 南京先进生物材料与过程装备研究院有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-109200052-A | A kind of taxol and Fluorenone class STAT3 inhibitor drug combination compositions | 南京先进生物材料与过程装备研究院有限公司 | 2019-01-15 | — | — | CN | claimed |
| CN-103360249-B | To acetoxyl methyl phenyl carbinol and the preparation method to acetoxystyrene | SINOPEC CORP. (CN) | 2015-12-02 | — | — | CN | claimed |
| CN-102452935-B | Preparation method of p-acetoxyacetophenone, and hydrogenation and dehydration products thereof | CHINA PETROLEUM & CHEMICAL | 2014-03-05 | — | — | CN | claimed |
| CN-103360249-A | Preparation methods of acetate alpha-phenethyl alcohol and acetate styrene | CHINA PETROLEUM & CHEMICAL | 2013-10-23 | — | — | CN | claimed |
| CN-102795999-A | Preparation method of p-acetoxystyrene and preparation method of its intermediate | HENAN NEWLAND PHARM CO LTD | 2012-11-28 | — | — | CN | claimed |
| CN-102452935-A | Preparation method of p-acetophenone acetate and hydrogenation and dehydration products thereof | CHINA PETROLEUM & CHEMICAL | 2012-05-16 | — | — | CN | claimed |
| CN-102093216-A | Method for preparing p-acetoxyacetophenone and o-acetoxyacetophenone | RIQING CAO | 2011-06-15 | — | — | CN | claimed |
| EP-0365340-A2 | Copolymers of 4-hydroxystyrene and alkyl substituted-4-hydroxystyrene | HOECHST CELANESE CORPORATION (US) | 1990-04-25 | — | — | EP | claimed |
| EP-0356070-A1 | Synthesis of 4-acetoxystyrene oxide and related compounds | HOECHST CELANESE CORPORATION (US) | 1990-02-28 | — | — | EP | claimed |
| US-4469883-A | Palladium catalyzed oxy-acetylation of phenyl acetate to meta-acetoxyacetophenone | SUN TECH, INC. (US) | 1984-09-04 | — | — | US | claimed |
| US-4054719-A | ACRYLIC ESTER, TERTIARY AMINE | AMERICAN CYANAMID COMPANY (US) | 1977-10-18 | — | — | US | claimed |