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SCHEMBL19072275

SCHEMBL19072275

O=P(c1ccccc1)(c1ccccc1)c1cccc(-c2ccc3c(c2)[Si](c2ccccc2)(c2ccccc2)c2ccccc2N3c2ccccc2)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 2/20 0.33
▸ MGLL Q99685 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ PDE6D O43924 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20022912 0.81 ALDH1A1 (0.44) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL20022913 0.81 PDE6D (0.39) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL20022897 0.81 MGLL (0.42) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL24555255 0.81 FAAH (0.31) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL24555248 0.81 FAAH (0.31) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL24555256 0.81 FAAH (0.31) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL24555277 0.80 FAAH (0.30) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL16017498 0.79 ALDH1A1 (0.47) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL24555067 0.79 FAAH (0.31) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL24555171 0.79 FAAH (0.31) FAAHMGLLALDH1A1HSP90AA1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2705550-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-07-05 — — EP disclosed
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