Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5581998 | 0.87 | FFAR1 (0.56) | LMNACA2CA1FFAR1FFAR4 | |
| SCHEMBL5908733 | 0.84 | ALDH1A1 (0.51) | LMNAALDH1A1CA2CA1STS | |
| SCHEMBL2257211 | 0.82 | F2RL1 (0.46) | LMNAALDH1A1CXCR2FFAR1CXCR1 | |
| SCHEMBL6941010 | 0.82 | PPARA (0.51) | CA2CA1STSCXCR2CXCR1 | |
| SCHEMBL26619697 | 0.80 | HTR1A (0.52) | CA2CA1HTR1AHTR1DHTR1B | |
| SCHEMBL17847695 | 0.80 | CA2 (0.46) | CA2CA1STSCXCR2CXCR1 | |
| SCHEMBL17834378 | 0.80 | PPARA (0.41) | LMNACA2CA1STSCXCR2 | |
| SCHEMBL5723863 | 0.79 | EPHX1 (0.50) | LMNAALDH1A1FFAR1FFAR4 | |
| SCHEMBL4461203 | 0.77 | CA2 (0.47) | LMNACA2STSCXCR2CXCR1 | |
| SCHEMBL7771915 | 0.77 | CA2 (0.44) | ALDH1A1CA2CA1STSCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101912382-B | 2-phenylpropionic acid derivatives and pharmaceutical compositions containing them | DOMPE SPA | 2012-11-21 | — | — | CN | disclosed |
| EP-2493846-A1 | 2-ARYL-PROPIONAMIDE DERIVATIVES USEFUL AS BRADYKININ RECEPTOR ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompe S.p.A. (IT) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051375-A1 | 2-ARYL-PROPIONAMIDE DERIVATIVES USEFUL AS BRADYKININ RECEPTOR ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.p.A. (IT) | 2011-05-05 | — | — | WO | disclosed |