Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074563 | 0.91 | NOTUM (0.37) | HSD17B10NOTUMHPDHPGDLMNA | |
| SCHEMBL18707647 | 0.90 | NOTUM (0.39) | HSD17B10NOTUMHPDHPGDLMNA | |
| SCHEMBL1081059 | 0.85 | SMN1; SMN2 (0.41) | NOTUMHPGDLMNACYP1A2CYP2D6 | |
| SCHEMBL1074776 | 0.85 | NOTUM (0.36) | HSD17B10NOTUMHPGDLMNAL3MBTL1 | |
| SCHEMBL1900602 | 0.84 | TDP2 (0.42) | HSD17B10NOTUMHPGDLMNACYP1A2 | |
| SCHEMBL1074771 | 0.83 | POLB (0.39) | HPGDLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1903822 | 0.82 | GAA (0.36) | NOTUMHPGDLMNACYP1A2CYP2D6 | |
| SCHEMBL1908180 | 0.79 | GAA (0.35) | HPDHPGDLMNACYP1A2CYP2D6 | |
| SCHEMBL1074544 | 0.78 | KDM4E (0.35) | HSD17B10NOTUMHPGDLMNAKDM4E | |
| SCHEMBL1074571 | 0.78 | NOTUM (0.39) | HSD17B10NOTUMHPDHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056463-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |