Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 4/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HPD | P32754 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903822 | 0.87 | GAA (0.36) | GAAHPGDVCPPTGS2CYP1A2 | |
| SCHEMBL1081059 | 0.84 | SMN1; SMN2 (0.41) | GAAHPGDSMN1; SMN2RXRAGRIN1 | |
| SCHEMBL1900602 | 0.83 | TDP2 (0.42) | GAAHPGDTDP2PTGS2CYP1A2 | |
| SCHEMBL1074563 | 0.82 | NOTUM (0.37) | GAAHPGDPTGS2CYP1A2CYP2D6 | |
| SCHEMBL18707647 | 0.81 | NOTUM (0.39) | GAAHPGDSMN1; SMN2PTGS2CYP1A2 | |
| SCHEMBL1907768 | 0.79 | HSD17B10 (0.39) | GAAHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1074776 | 0.77 | NOTUM (0.36) | GAAHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1074700 | 0.76 | CACNA2D1 (0.38) | GAAHPGDVCPSMN1; SMN2PTGS2 | |
| SCHEMBL1906802 | 0.76 | VCP (0.34) | GAAVCPRXRAGRIN1GRIN2B | |
| SCHEMBL1903762 | 0.76 | HCRTR1 (0.38) | RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056463-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |