Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074563 | 0.88 | NOTUM (0.37) | PTGS2NOTUMHPGDKDM4ECYP1A2 | |
| SCHEMBL18707647 | 0.87 | NOTUM (0.39) | PTGS2NOTUMHPGDKDM4ECYP1A2 | |
| SCHEMBL1905621 | 0.86 | TDP2 (0.38) | TDP2EGLN2PTGS1PTGS2PIK3CD | |
| SCHEMBL1908385 | 0.86 | EGLN2 (0.34) | EGLN2GRM5PIK3CDHPGDCYP1A2 | |
| SCHEMBL1076165 | 0.84 | POLB (0.36) | TDP2EGLN2GRM5PIK3CDKDM4E | |
| SCHEMBL1907768 | 0.84 | HSD17B10 (0.39) | NOTUMHPGDKDM4ECYP1A2CYP2D6 | |
| SCHEMBL1904874 | 0.84 | TDP2 (0.40) | TDP2EGLN2PTGS1PTGS2GRM5 | |
| SCHEMBL1908180 | 0.83 | GAA (0.35) | TDP2PTGS1PTGS2GRM5HPGD | |
| SCHEMBL1081059 | 0.82 | SMN1; SMN2 (0.41) | NOTUMHPGDKDM4ECYP1A2CYP2D6 | |
| SCHEMBL1902028 | 0.82 | GRM5 (0.45) | EGLN2GRM5PIK3CDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056463-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-12 | — | — | WO | claimed |
| WO-2011056463-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |