Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276820 | 0.91 | GAA (0.48) | GAAMAPTAKR1C3FAAH | |
| SCHEMBL19078771 | 0.87 | AKR1C3 (0.52) | AKR1C3 | |
| SCHEMBL20557099 | 0.86 | — | — | |
| SCHEMBL19078798 | 0.84 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL19078790 | 0.84 | AKR1C3 (0.62) | GAAMAPTAKR1C3 | |
| SCHEMBL19078805 | 0.82 | AKR1C3 (0.46) | AKR1C3FAAH | |
| SCHEMBL19078791 | 0.81 | AKR1C3 (0.54) | GAAMAPTAKR1C3 | |
| SCHEMBL21802553 | 0.81 | MAPT (0.53) | GAAMAPTAKR1C3 | |
| SCHEMBL21276334 | 0.81 | FAAH (0.47) | FAAH | |
| SCHEMBL19078775 | 0.80 | AKR1C3 (0.56) | AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, FAAH, FAAH2 | GAA 2974/4885MAPT 4504/4885AKR1C3 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.