SCHEMBL19080014

SCHEMBL19080014

c1cc(-c2ccc3c4ccccc4c4c(oc5c6ccccc6c6ccccc6c54)c3c2)cc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccccc23)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 0.40
CYP1B1 Q16678 6/20 0.40
HSD17B1 P14061 3/20 0.40
HSD17B2 P37059 3/20 0.40
CYP1A2 P05177 8/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
THRB P10828 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP19A1 P11511 3/20 0.35
CYP17A1 P05093 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
CYP3A4 P08684 3/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2C9 P11712 3/20 0.35
CYP2B6 P20813 3/20 0.35
CYP2C19 P33261 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19080114 0.93 CYP1A1 (0.43) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL19080013 0.91 CYP1A1 (0.43) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL19080011 0.91 CYP1A1 (0.46) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL19079998 0.90 CYP1A1 (0.41) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL19080005 0.90 CYP1A1 (0.40) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL19080044 0.89 ESR1 (0.38) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL19079946 0.89 PLA2G2A (0.40) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL23502288 0.87 CYP1A1 (0.37) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL17931951 0.87 CYP1A1 (0.37) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2
SCHEMBL17931928 0.87 CYP1A1 (0.37) CYP1A1CYP1B1HSD17B1HSD17B2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10580999-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-03 US disclosed
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNA1 CYP1A1 147/4885CYP1B1 225/4885HSD17B1 733/4885
US-10580999-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNA1 CYP1A1 147/4885CYP1B1 225/4885HSD17B1 733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.