SCHEMBL19080168

SCHEMBL19080168

c1cc(-c2c3ccccc3c(-c3cccc4c3oc3ccccc34)c3ccccc23)cc(-c2cc3c4cc5ccccc5cc4oc3c3ccccc23)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.45
GGPS1 O95749 1/20 0.39
PRKDC P78527 6/20 0.37
PTGES2 Q9H7Z7 1/20 0.37
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
DYRK1A Q13627 1/20 0.34
AHR P35869 2/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
ATM Q13315 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21450845 0.90 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL19076371 0.88 ALOX5 (0.42) ALOX5GGPS1PRKDCPTGES2DYRK1A
SCHEMBL22707591 0.88 ALOX5 (0.40) ALOX5GGPS1PRMT5WDR77ATM
SCHEMBL10122479 0.88 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2DYRK1A
SCHEMBL20127568 0.87 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL16067674 0.87 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL24285720 0.86 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL20127553 0.86 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL16067683 0.86 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL10122483 0.86 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNA1 ALOX5 1871/4885GGPS1 357/4885PRKDC 4792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.