SCHEMBL19081535

SCHEMBL19081535

c1ccc2c(-c3c4ccccc4c(-c4ccc(-c5ccc6c(c5)oc5ccc7oc8c9ccccc9ccc8c7c56)cc4)c4ccccc34)cccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 10/20 0.36
CYP1B1 Q16678 10/20 0.36
PSD A5PKW4 1/20 0.35
CYP1A2 P05177 9/20 0.35
CYP3A4 P08684 2/20 0.35
TSHR P16473 2/20 0.35
CYP2C19 P33261 2/20 0.35
PRKDC P78527 2/20 0.35
KDM4E B2RXH2 1/20 0.35
PDE5A O76074 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
ABCB1 P08183 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP19A1 P11511 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2B6 P20813 1/20 0.35
TACR2 P21452 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19081663 0.94 CYP1A1 (0.41) CYP1A1CYP1B1PSDCYP1A2CYP3A4
SCHEMBL19081557 0.94 CYP1A1 (0.37) CYP1A1CYP1B1PSDCYP1A2CYP3A4
SCHEMBL19076310 0.92 TDP1 (0.37) CYP1A1CYP1B1PSDALDH1A1ABCB1
SCHEMBL19081533 0.92 ARSA (0.36) CYP1A1CYP1B1PSDCYP1A2CYP3A4
SCHEMBL19081647 0.92 ARSA (0.38) CYP1A1CYP1B1PSDCYP1A2CYP3A4
SCHEMBL17944123 0.90 HCRTR1 (0.39) PSDALDH1A1MAPTHPGDHSD17B10
SCHEMBL17931929 0.90 ALOX5 (0.40) CYP1A1CYP1B1PSDCYP1A2CYP3A4
SCHEMBL19081500 0.90 CYP1A1 (0.44) CYP1A1CYP1B1CYP1A2CYP3A4TSHR
SCHEMBL17944985 0.90 TDP1 (0.38) CYP1A1PSDCYP1A2CYP3A4CYP2C19
SCHEMBL19081534 0.89 ALOX5 (0.36) CYP1A1PSDCYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 CYP1A1 184/4885CYP1B1 260/4885PSD 3197/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 CYP1A1 184/4885CYP1B1 260/4885PSD 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.