SCHEMBL19081943

SCHEMBL19081943

c1cc(-c2ccc3oc4c(ccc5sc6c7ccccc7ccc6c54)c3c2)cc(-c2c3ccccc3c(-c3cccc4ccccc34)c3ccccc23)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 0.35
CYP1B1 Q16678 5/20 0.35
CYP1A2 P05177 4/20 0.33
ALOX5 P09917 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPK1 P28482 1/20 0.32
MAPT P10636 5/20 0.31
ALDH1A1 P00352 4/20 0.31
KDM4E B2RXH2 3/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PLA2G10 O15496 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
PIM1 P11309 2/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19076974 0.91 ALOX5 (0.41) CYP1A1CYP1B1CYP1A2ALOX5
SCHEMBL19076821 0.90 ALOX5 (0.37) CYP1A1CYP1B1CYP1A2ALOX5MAPT
SCHEMBL19081761 0.90 CYP1A1 (0.39) CYP1A1CYP1B1CYP1A2KMT2AMAPK1
SCHEMBL19081942 0.89 CYP1A1 (0.37) CYP1A1CYP1B1CYP1A2ALOX5KMT2A
SCHEMBL19081775 0.89 ALOX5 (0.34) CYP1A1CYP1A2ALOX5KMT2AMAPK1
SCHEMBL19081819 0.89 CYP1A1 (0.38) CYP1A1CYP1B1CYP1A2KMT2AMAPK1
SCHEMBL19076685 0.88 ALOX5 (0.37) CYP1A1CYP1B1CYP1A2ALOX5MAPT
SCHEMBL19082052 0.88 ALOX5 (0.32) CYP1A1CYP1B1CYP1A2ALOX5KMT2A
SCHEMBL19081805 0.87 CYP1A1 (0.38) CYP1A1CYP1B1CYP1A2KMT2AMAPT
SCHEMBL19081945 0.87 AHR (0.33) CYP1A1CYP1A2KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 CYP1A1 184/4885CYP1B1 260/4885CYP1A2 659/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 CYP1A1 184/4885CYP1B1 260/4885CYP1A2 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.