SCHEMBL19082314

SCHEMBL19082314

c1cc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccccc23)cc(-c2cc3c(sc4ccc5ccccc5c43)c3sc4ccccc4c23)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
PTPN1 P18031 2/20 0.35
S1PR5 Q9H228 8/20 0.35
S1PR4 O95977 6/20 0.35
NQO1 P15559 1/20 0.33
NQO2 P16083 1/20 0.33
GSTP1 P09211 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1B1 Q16678 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
PTPRC P08575 1/20 0.30
PTPRF P10586 1/20 0.30
PTPRA P18433 1/20 0.30
PTPRB P23467 1/20 0.30
PTPN6 P29350 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082172 0.94 PTPN1 (0.34) ALOX5PTPN1S1PR5S1PR4NQO1
SCHEMBL19082386 0.92 ALOX5 (0.37) ALOX5PTPN1S1PR5S1PR4NQO1
SCHEMBL17944217 0.91 ALOX5 (0.40) ALOX5PTPN1S1PR5S1PR4GSTP1
SCHEMBL19082232 0.89 PTPN1 (0.38) ALOX5PTPN1NQO1NQO2CYP1A1
SCHEMBL19082313 0.88 ALOX5 (0.34) ALOX5PTPN1S1PR5S1PR4NQO1
SCHEMBL19077367 0.86 ALOX5 (0.39) ALOX5PTPN1S1PR5S1PR4GSTP1
SCHEMBL17945340 0.86 ALOX5 (0.42) ALOX5S1PR5S1PR4NQO1NQO2
SCHEMBL19082250 0.85 ALOX5 (0.36) ALOX5PTPN1NQO1NQO2PTPRC
SCHEMBL19082310 0.85 NQO1 (0.34) ALOX5PTPN1S1PR5S1PR4NQO1
SCHEMBL17944206 0.85 ALOX5 (0.37) ALOX5PTPN1S1PR5S1PR4GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 ALOX5 1939/4885PTPN1 4695/4885S1PR5 4728/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 ALOX5 1939/4885PTPN1 4695/4885S1PR5 4728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.