SCHEMBL19082492

SCHEMBL19082492

COc1cc(C)c(-c2cc(Br)ccc2F)cc1-c1c(F)ccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
NPC1 O15118 2/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
RAB9A P51151 2/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ACHE P22303 1/20 0.38
ABCG2 Q9UNQ0 3/20 0.34
ABCC1 P33527 1/20 0.34
TSHR P16473 1/20 0.34
RRM1 P23921 2/20 0.33
NMUR2 Q9GZQ4 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
ALOX5 P09917 2/20 0.33
PTGES O14684 1/20 0.33
TP53 P04637 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19091030 0.92 MAPT (0.44) MAPTNPC1HTTKMT2AMEN1
SCHEMBL19082499 0.82 NMUR2 (0.34) NPC1HTTNMUR2ALOX5PTGES
SCHEMBL18842457 0.81 MAPT (0.57) MAPTNPC1HTTKMT2AMEN1
SCHEMBL19091609 0.81 MAPT (0.39) MAPTNPC1HTTKMT2AMEN1
SCHEMBL19082466 0.79 NMUR2 (0.38) MAPTNPC1HTTRAB9ATSHR
SCHEMBL19082490 0.76 NMUR2 (0.43) MAPTNPC1KMT2AMEN1SMN1; SMN2
SCHEMBL16067917 0.76 NPC1 (0.50) MAPTNPC1HTTKMT2AMEN1
SCHEMBL19082493 0.75 MAPT (0.42) MAPTKMT2AMEN1RAB9AALDH1A1
SCHEMBL19082495 0.75 NMUR2 (0.37) NPC1HTTNMUR2PTGESTP53
SCHEMBL16067924 0.75 NPC1 (0.41) MAPTNPC1HTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 MAPT 1294/4885NPC1 1508/4885HTT 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.