Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19082577 | 0.83 | THRB (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL19975589 | 0.82 | THRB (0.41) | THRBTSHRALDH1A1 | |
| SCHEMBL19082572 | 0.82 | TSHR (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL19082588 | 0.80 | TSHR (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL9162165 | 0.77 | TSHR (0.40) | THRBTSHRALDH1A1 | |
| SCHEMBL1636583 | 0.75 | TSHR (0.52) | THRBTSHRALDH1A1 | |
| SCHEMBL1636584 | 0.75 | TSHR (0.52) | THRBTSHRALDH1A1 | |
| SCHEMBL5654625 | 0.75 | TSHR (0.52) | THRBTSHRALDH1A1 | |
| SCHEMBL6014149 | 0.74 | THRB (0.43) | THRBTSHRALDH1A1 | |
| SCHEMBL35935 | 0.73 | TSHR (0.40) | THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920080-B2 | Alkoxysilyl-vinylene group-containing silicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-03-20 | — | — | US | disclosed |
| US-20170190721-A1 | ALKOXYSILYL-VINYLENE GROUP-CONTAINING SILICON COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190721-A1 | ALKOXYSILYL-VINYLENE GROUP-CONTAINING SILICON COMPOUND | VCAM1, VIM, ICAM1 | THRB 2767/4885TSHR 3711/4885ALDH1A1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.