SCHEMBL19083038

SCHEMBL19083038

CC(C)c1cccc(C(C)C)c1-c1ccc2c(-c3cc(C(F)(F)F)n[nH]3)nccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 12/20 0.35
USP1 O94782 1/20 0.33
WDR48 Q8TAF3 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
GLA P06280 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SCN9A Q15858 3/20 0.32
ITGB2 P05107 2/20 0.31
ICAM1 P05362 2/20 0.31
ITGAL P20701 2/20 0.31
SCN5A Q14524 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15671658 0.80 IDO1 (0.35) USP1WDR48CYP1A2NR1H2NR1H3
SCHEMBL15871669 0.77 GRM4 (0.38) GRM4CYP1A2CYP2C19KDM4ENPC1
SCHEMBL20224623 0.76 ITGB2 (0.33) USP1WDR48NR1H2NR1H3ITGB2
SCHEMBL2948463 0.76 KDM4E (0.51) GRM4CYP1A2CYP2C19KDM4ENPC1
SCHEMBL19083039 0.75 KIF11 (0.38) GRM4CYP1A2CYP2C19KMT2ASCN9A
SCHEMBL23751341 0.71 MAP4K4 (0.56)
SCHEMBL31552437 0.70 JAK2 (0.44)
SCHEMBL23066763 0.70 JAK2 (0.44)
SCHEMBL15871661 0.68 GRM4 (0.32) GRM4CYP1A2CYP2C19NPSR1
SCHEMBL18678819 0.66 PDPK1 (0.44) GRM4CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-07-06 US disclosed
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME OCIAD2, POF1B, OCIAD1 GRM4 813/4885USP1 4274/4885WDR48 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.