SCHEMBL2948463

SCHEMBL2948463

FC(F)(F)c1cc(-c2nccc3ccccc23)[nH]n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.51
MAPT P10636 2/20 0.51
KMT2A Q03164 2/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
GLA P06280 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
PTGS2 P35354 1/20 0.42
CNR2 P34972 3/20 0.40
MAPK1 P28482 1/20 0.40
NPY5R Q15761 1/20 0.39
GRM4 Q14833 5/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
CYP2A6 P11509 1/20 0.37
F12 P00748 1/20 0.37
PLAU P00749 1/20 0.37
NCF1 P14598 1/20 0.37
NOS3 P29474 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2945434 0.86 KDM4E (0.51) KDM4EMAPTKMT2ANPC1RAB9A
SCHEMBL15871669 0.82 GRM4 (0.38) KDM4EMAPTKMT2ANPC1RAB9A
SCHEMBL24716058 0.82 KDM4E (0.56) KDM4EMAPTKMT2ANPC1RAB9A
SCHEMBL19083039 0.80 KIF11 (0.38) KMT2AGRM4CYP1A2CYP2C19ALDH1A1
SCHEMBL15508105 0.77 ADORA2A (0.45) RAB9AMAPK1GRM4ADRB2
SCHEMBL31019645 0.77 HSD17B10 (0.43) KDM4EMAPTKMT2ARAB9AL3MBTL1
SCHEMBL18287245 0.77 HSD17B10 (0.43) KDM4EMAPTKMT2ARAB9AL3MBTL1
SCHEMBL19676856 0.76 PDPK1 (0.40) KMT2AGRM4CYP1A2CYP2C19BACE1
SCHEMBL28157694 0.76 PTGS2 (0.45) KDM4EMAPTKMT2ANPC1RAB9A
SCHEMBL19083038 0.76 GRM4 (0.35) KDM4EMAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107210377-B Varnish for forming charge-transporting thin film 日产化学工业株式会社 2019-07-05 CN disclosed
CN-106663741-B Charge-transporting material 日产化学工业株式会社 2019-06-28 CN disclosed
US-20190058132-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-21 US disclosed
CN-107710440-A Charge-transporting varnish and organic electroluminescent element 日产化学工业株式会社 2018-02-16 CN disclosed
CN-107428676-A Anil and its utilization 日产化学工业株式会社 2017-12-01 CN disclosed
CN-107406584-A Fluorine atom-containing polymer and field of use thereof 日产化学工业株式会社 2017-11-28 CN disclosed
CN-107408637-A Charge-transporting film for organic electroluminescent device forms composition, charge-transporting film and organic electroluminescent device for organic electroluminescent device 日产化学工业株式会社 2017-11-28 CN disclosed
CN-105612628-B Charge-transporting varnish 日产化学工业株式会社 2017-10-27 CN disclosed
CN-105612146-B Aryl sulfonic acid compound and its utilization and the preparation method of aryl sulfonic acid compound 日产化学工业株式会社 2017-10-27 CN disclosed
CN-107210377-A Varnish for forming charge-transporting thin film 日产化学工业株式会社 2017-09-26 CN disclosed
CN-105324370-A Thiophene derivative, use thereof, and production method of thiophene derivative NISSAN CHEMICAL IND LTD 2016-02-10 CN disclosed
CN-105210207-A Charge-transporting varnish NISSAN CHEMICAL IND LTD 2015-12-30 CN disclosed
CN-104629591-A Charge-transporting varnish, charge-transporting thin film, and organic electroluminescent device NISSAN CHEMICAL IND LTD 2015-05-20 CN disclosed
CN-104513513-A Charge transfer varnish, charge transfer thin film and organic electroluminescence component NISSAN CHEMICAL IND LTD 2015-04-15 CN disclosed
CN-104513512-A Charge transfer varnish, charge transfer thin film and organic electroluminescence component NISSAN CHEMICAL IND LTD 2015-04-15 CN disclosed
CN-104517665-A Charge transporting varnish, charge transporting thin film, organic electroluminescent device and manufacturing method for charge transporting thin film NISSAN CHEMICAL IND LTD 2015-04-15 CN disclosed
US-8779134-B1 Six-coordinated ruthenium complex NATIONAL TSING HUA UNIVERSITY (TW) 2014-07-15 US disclosed
US-7759490-B2 Phosphorescent Osmium (II) complexes and uses thereof NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2010-07-20 US disclosed
US-20090058281-A1 organic light emitting diodes; plasma enchanced chemical vapor deposition; metal organic chemical vapor deposition SAMSUNG DISPLAY CO., LTD. (KR) 2009-03-05 US disclosed
US-20070001166-A1 Phosphorescent Osmium (II) complexes and uses thereof TAO YE 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070001166-A1 Phosphorescent Osmium (II) complexes and uses thereof OCIAD2, OCIAD1, ORC3 KDM4E 4048/4885MAPT 4394/4885KMT2A 3946/4885
US-20090058281-A1 organic light emitting diodes; plasma enchanced chemical vapor deposition; metal organic chemical vapor deposition SDC4, C9, SDC1 KDM4E 2031/4885MAPT 3737/4885KMT2A 3367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.